7-Fluoro-4-iodo-1H-indole CAS 1360883-26-6
| CAS No. | 1360883-26-6 |
| Molecular Formula | C8H5FIN |
| Molecular Weight | 261.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-Fluoro-4-iodo-1H-indole (CAS 1360883-26-6), molecular formula C8H5FIN and molecular weight 261.03 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 7-Fluoro-4-iodo-1H-indole (C8H5FIN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Fluoro-4-iodo-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5FIN |
| Molecular Weight | 261.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 4-Fluoro-7-iodo-1H-indole (CAS 1000341-66-1)
- 4-Fluoro-5-iodo-1H-indole (CAS 1240113-40-9)
- 2-(3-Fluoro-2-iodophenyl)acetonitrile (CAS 1261744-72-2)
- 3-Fluoro-5-iodo-4-methylbenzonitrile (CAS 1357624-09-9)
- 7-Fluoro-3-iodo-1H-indole (CAS 1360956-39-3)
- 5-fluoro-2-iodo-1H-indole (CAS 1388045-67-7)
- 5-Fluoro-7-iodo-1H-indole (CAS 1774896-43-3)
- 2-(2-Fluoro-4-iodophenyl)acetonitrile (CAS 345963-95-3)
Recommended Standards
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- 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)cyclopropane-1-carbonitrile (CAS 1094379-66-4)
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