3-Methyl-4-(trifluoromethyl)-1H-indole CAS 1360922-90-2
| CAS No. | 1360922-90-2 |
| Molecular Formula | C10H8F3N |
| Molecular Weight | 199.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Methyl-4-(trifluoromethyl)-1H-indole (C10H8F3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
3-Methyl-4-(trifluoromethyl)-1H-indole (CAS 1360922-90-2) is a high-purity analytical reference standard with the molecular formula C10H8F3N and a molecular weight of 199.17 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Methyl-4-(trifluoromethyl)-1H-indole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8F3N |
| Molecular Weight | 199.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 2-(2-Methyl-5-(trifluoromethyl)phenyl)acetonitrile (CAS 1000513-69-8)
- 2-(2-Methyl-3-(trifluoromethyl)phenyl)acetonitrile (CAS 1000515-00-3)
- 2-(4-Methyl-3-(trifluoromethyl)phenyl)acetonitrile (CAS 1000526-63-5)
- 3-Methyl-5-(trifluoromethyl)-1H-indole (CAS 1004547-95-8)
- 2-(5-Methyl-2-(trifluoromethyl)phenyl)acetonitrile (CAS 1017778-24-3)
- 2-Methyl-4-(trifluoromethyl)-1H-indole (CAS 1018971-85-1)
- 6-Methyl-2-(trifluoromethyl)-1H-indole (CAS 1067188-90-2)
- 2-(2-(Trifluoromethyl)phenyl)propanenitrile (CAS 1096308-46-1)
Recommended Standards
- 7-Methyl-6-(trifluoromethyl)-1H-indole (CAS 1360885-98-8)
- 6-Nitroquinoline-2-carbonitrile (CAS 13675-93-9)
- 2-Amino-4-methyl-2-(trifluoromethyl)pentanoic acid (CAS 136030-50-7)
- 8-Nitro-5-quinolinecarbonitrile (CAS 1394085-55-2)
- N-(2-Bromophenyl)-2-((4-ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 577984-00-0)
- Sapropterin Hydrochloride (CAS 69056-38-8)
- 5-(Cyanomethyl)-4-(difluoromethyl)-3-fluoropicolinonitrile (CAS 1805414-88-3)
- (Carboxyalkyl)TerminatedPolyDimethylsiloxane (CAS 158465-59-9)
- Benzyl (3,3-dimethyl-1-(pyrrolidin-1-yl)butan-2-yl)(methyl)carbamate (CAS 886363-08-2)
- 2-(Chloromethyl)-6-(difluoromethyl)-3-iodo-5-methoxypyridine (CAS 1806983-11-8)
- 1-carbamoylpiperidine-2-carboxylic acid (CAS 141102-33-2)
- 1-Allyl-3-(2-chloro-acetyl)-urea (CAS 5544-34-3)
- 3-Chloro-N-(2-isopropylphenyl)propanamide (CAS 560078-34-4)
- Semaglutide impurity 249 (CAS CATO-C4X-2226249)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com