5-Bromo-4-fluoro-1h-indazole-3-carboxylicacid CAS 1360958-33-3
| CAS No. | 1360958-33-3 |
| Molecular Formula | C8H4BrFN2O2 |
| Molecular Weight | 259.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Bromo-4-fluoro-1h-indazole-3-carboxylicacid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Bromo-4-fluoro-1h-indazole-3-carboxylicacid (CAS 1360958-33-3), a certified reference material (molecular formula C8H4BrFN2O2, MW 259.03 g/mol) for analytical method development and quality control.
5-Bromo-4-fluoro-1h-indazole-3-carboxylicacid (C8H4BrFN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Bromo-4-fluoro-1h-indazole-3-carboxylicacid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4BrFN2O2 |
| Molecular Weight | 259.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- (2-Bromo-4-fluoro-6-nitro-phenyl)-acetonitrile (CAS 1082040-49-0)
- 5-Bromo-7-fluorobenzofuran-2-carboxylic acid (CAS 1249506-21-5)
- 6-Bromo-8-fluoroimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1260784-00-6)
- 6-Bromo-3-fluoroimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1279219-30-5)
- 5-Bromo-6-fluoro-1H-indazole-3-carboxylic acid (CAS 1360928-47-7)
- 5-Bromo-7-fluoro-1h-indazole-3-carboxylicacid (CAS 1360953-31-6)
- 7-Bromo-6-fluoroquinazoline-2,4(1H,3H)-dione (CAS 1374208-43-1)
- 8-Bromo-6-fluoroimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1421312-07-3)
Recommended Standards
- 5-Bromo-7-fluorobenzofuran-3-carboxylic acid (CAS 1479026-17-9)
- 5-Bromo-7-fluoro-1,4-dihydroquinoxaline-2,3-dione (CAS 153504-80-4)
- (2-(Pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)boronic acid (CAS 1704063-76-2)
- (3-(Pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)boronic acid (CAS 1704067-30-0)
- 2,5-Bis(3,7-dimethyloctyloxy)terephthalaldehyde (CAS 325461-35-6)
- 1,3-Bis(2,6-di-i-propylphenyl)imidazolidin-2-ylidene)(2-i-propoxy-5-nitrobenzylidene) ruthenium(II) dichloride (CAS 928795-51-1)
- 4,5-Diamino-2-(difluoromethyl)nicotinaldehyde (CAS 1805236-38-7)
- Perfluoro-2,5,8,11,14,17,20-heptamethyl-3,6,9,12,15,18,21-heptaoxatetracosanoyl fluoride (CAS 13140-25-5)
- (1R)-2,2',3,3'-Tetrahydro-6,6'-bis[2,4,6-tris(1-methylethyl)phenyl]-1,1'-spirobi[1H-indene]-7,7'-diol (CAS 1372719-98-6)
- Undecanehydrazide (CAS 45135-30-6)
- Tamsulosin Impurity 19 (CAS 116091-63-5)
- Alizarin (CAS 72-48-0)
- Norepinephrine Impurity 136 (CAS CATO-C4X-1514136)
- [3-31]-Semaglutide D (Sodium salt) (CAS CATO-C4X-2226119)
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