Pyrazolo[1,5-a]pyridine-4-carbonitrile CAS 1361004-15-0
| CAS No. | 1361004-15-0 |
| Molecular Formula | C8H5N3 |
| Molecular Weight | 143.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 143.15 g/mol gives Pyrazolo[1,5-a]pyridine-4-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Pyrazolo[1,5-a]pyridine-4-carbonitrile (CAS 1361004-15-0), molecular formula C8H5N3 and molecular weight 143.15 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Pyrazolo[1,5-a]pyridine-4-carbonitrile (C8H5N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5N3 |
| Molecular Weight | 143.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
Related Pyrazolo Standards
- Pyrazolo[1,5-a]pyridine-7-carbonitrile (CAS 319432-36-5)
- 1H-pyrazolo[3,4-b]pyridin-5-ol (CAS 1256818-99-1)
- 1H-pyrazolo[4,3-d]pyrimidin-7-amine (CAS 13877-56-0)
- 1H-pyrazolo[3,4-b]pyridin-4-ol (CAS 49834-67-5)
- 1H-pyrazolo[3,4-b]pyridin-6-ol (CAS 61514-61-2)
- pyrazolo[1,5-b]pyridazin-6-ol (CAS 2411637-09-5)
- 1H-pyrazolo[3,4-c]pyridin-5-amine (CAS 1049672-75-4)
- 1H-pyrazolo[4,3-c]pyridin-4-amine (CAS 1159829-57-8)
Recommended Standards
- 1H-Pyrrolo[3,2-c]pyridine-7-carbonitrile (CAS 1352393-68-0)
- Imidazo[1,5-a]pyridine-8-carbonitrile (CAS 1369807-21-5)
- 6-Methyl-2,5-pyridinedicarbonitrile (CAS 1352318-05-8)
- 6-ETHYNYLIMIDAZO[1,2-A]PYRAZINE (CAS 1372096-41-7)
- 2-Chlor-4'-methyl-biphenyl (CAS 19493-33-5)
- 2-{5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazol-3-yl}pyridine dihydrochloride (CAS 2059949-19-6)
- 1-(3-Isothiocyanato-propyl)-3,5-dimethyl-1h-pyrazole (CAS 1004643-59-7)
- 2-(2-Bromophenyl)-N-(1-(3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)cyclohexyl)acetamide (CAS 1396634-11-9)
- 2-(Cyanomethyl)benzo[d]oxazole-5-sulfonyl chloride (CAS 1806280-70-5)
- Tert-butyl 2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)pyrrolidine-1-carboxylate (CAS 1610376-95-8)
- Methyl 4-amino-3-(4-nitrophenyl)isothiazole-5-carboxylate (CAS 100361-49-7)
- 1-(1H-Benzo[d]imidazol-2-yl)-6-styryl-1,5,6,7-tetrahydro-4H-indazol-4-one (CAS 924864-46-0)
- (7-Chloro-Benzo[1,3]Dioxol-5-Yl)-Methanol (CAS 179110-08-8)
- Vialox Peptide(Pentapeptide-3) (CAS 135679-88-8)
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