Morpholine-2-carboxylic acid [2-(3,5-dimethyl-1H-pyrazol-4-yl)-ethyl]-amide dihydrochloride CAS 1361111-31-0
| CAS No. | 1361111-31-0 |
| Molecular Formula | C12H20N4O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Morpholine-2-carboxylic acid [2-(3,5-dimethyl-1H-pyrazol-4-yl)-ethyl]-amide dihydrochloride.
Morpholine-2-carboxylic acid [2-(3,5-dimethyl-1H-pyrazol-4-yl)-ethyl]-amide dihydrochloride (CAS 1361111-31-0), molecular formula C12H20N4O2HCl and molecular weight 288.78 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Morpholine-2-carboxylic acid [2-(3,5-dimethyl-1H-pyrazol-4-yl)-ethyl]-amide dihydrochloride (C12H20N4O2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H20N4O2 2*HCl |
| Molecular Weight | 288.78 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Morpholine Standards
- Morpholine HCl (CAS 10024-89-2)
- 1-Ethyl-5-(morpholine-4-carbonyl)-1h-pyrazol-4-amine (CAS 1004643-31-5)
- 1-Methyl-3-(morpholine-4-carbonyl)-1h-pyrazole-5-carboxylic acid (CAS 1004727-34-7)
- 2-(4-(Morpholine-4-carbonyl)-1H-pyrazol-1-yl)acetic acid (CAS 1006468-66-1)
- 1-Methyl-3-(morpholine-4-carbonyl)-1H-pyrazole-4-carboxylic acid (CAS 1006491-12-8)
- Sodium 2-[5-(morpholine-4-sulfonyl)thiophen-2-yl]acetate (CAS 1007012-31-8)
- 7-(Morpholine-4-sulfonyl)-3-(propan-2-yl)-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 1007999-27-0)
- 1-[4-(morpholine-4-sulfonyl)-2-nitrophenyl]pyrrolidine-2-carboxylic acid (CAS 1008006-09-4)
Recommended Standards
- 4-Iodo-2,6-dimethyl-3-nitropyridine (CAS 91873-05-1)
- 4-(Heptyloxy)-3-methoxyaniline (CAS 15382-63-5)
- 4-(4-(Thiophen-2-yl)pyrimidin-2-yl)phenyl 3-methylbenzoate (CAS 477862-35-4)
- (R)-Methyl 5-iodo-2-(pyrrolidin-2-yl)benzoate (CAS 1217615-09-2)
- 5'-O-Trityl-2',3'-dehydrothymidine (CAS 5964-41-0)
- 1-Hydroxy-5-methoxyanthracene-9,10-dione (CAS 52869-21-3)
- 1-((5-Bromothiophen-2-yl)sulfonyl)-3-((furan-2-ylmethyl)sulfonyl)pyrrolidine (CAS 1798675-02-1)
- (E)-3-(2-((4-fluorobenzyl)oxy)phenyl)-3-oxopropanal O-(2,4-dichlorobenzyl) oxime (CAS 551931-28-3)
- 4-(3-Chloro-1-adamantyl)benzenesulfonyl chloride (CAS 1354356-42-5)
- Peptide 435 (CAS CATO-CPTD788435)
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