3-(5-Trifluoromethyl-1H-pyrazol-3-yl)-piperidine hydrochloride CAS 1361111-74-1
| CAS No. | 1361111-74-1 |
| Molecular Formula | C9H12F3N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(5-Trifluoromethyl-1H-pyrazol-3-yl)-piperidine hydrochloride is closely related to a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-(5-Trifluoromethyl-1H-pyrazol-3-yl)-piperidine hydrochloride (CAS 1361111-74-1), a certified reference material (molecular formula C9H12F3N3HCl, MW 255.67 g/mol) for analytical method development and quality control.
The molecular framework of 3-(5-Trifluoromethyl-1H-pyrazol-3-yl)-piperidine hydrochloride (C9H12F3N3HCl) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(5-Trifluoromethyl-1H-pyrazol-3-yl)-piperidine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12F3N3 HCl |
| Molecular Weight | 255.67 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidin-3-ol hydrochloride (CAS 1000198-74-2)
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1000198-76-4)
- (2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 1000339-72-9)
- methyl 3-((4-(trifluoromethyl)piperidin-1-yl)methyl)benzoate (CAS 1000339-86-5)
- methyl 4-(2-(4-(trifluoromethyl)piperidin-1-yl)ethoxy)benzoate (CAS 1000339-87-6)
- 2-(4-(trifluoromethyl)piperidin-1-yl)thiazole-5-carbaldehyde (CAS 1000339-88-7)
- 3-(2-(4-(trifluoromethyl)piperidin-1-yl)ethyl)benzaldehyde (CAS 1000339-89-8)
- 4-(2-(4-(trifluoromethyl)piperidin-1-yl)acetyl)-1H-pyrrole-2-carbaldehyde (CAS 1000339-90-1)
Recommended Standards
- 2-(3-(Benzo[d][1,3]dioxol-5-ylcarbamoyl)phenyl)acetic acid (CAS 860787-21-9)
- 2,2,2-Trifluoro-1-(3-fluorophenyl)ethanone (CAS 708-64-5)
- Ethyl 8-allyl-2-oxo-2H-chromene-3-carboxylate (CAS 250362-64-2)
- 1-(3-(Aminomethyl)tetrahydrofuran-3-yl)cyclopentan-1-ol (CAS 1504730-25-9)
- 3,3-dimethylbutyl methanesulfonate (CAS 69436-45-9)
- N-Prop-2-ynylhexanamide (CAS 62899-12-1)
- (R)-2-(((R)-tert-butylsulfinyl)amino)-2-(2-fluoro-5-nitrophenyl)-N-(4-methoxybenzyl)-N-methylpropane-1-sulfonamide (CAS 1286777-81-8)
- Ethyl 3-(tert-butyl)benzoate (CAS 62171-57-7)
- N-(Oxetan-3-yl)ethane-1,2-diamine (CAS 1343028-60-3)
- Semaglutide impurity 38 (CAS CATO-C4X-222638)
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