5-(Pyrrolidin-2-yl)-3-(trifluoromethyl)-1H-pyrazole hydrochloride CAS 1361111-76-3
| CAS No. | 1361111-76-3 |
| Molecular Formula | C8H10F3N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(Pyrrolidin-2-yl)-3-(trifluoromethyl)-1H-pyrazole hydrochloride is closely related to a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-(Pyrrolidin-2-yl)-3-(trifluoromethyl)-1H-pyrazole hydrochloride (CAS 1361111-76-3), molecular formula C8H10F3N3HCl and molecular weight 241.64 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-(Pyrrolidin-2-yl)-3-(trifluoromethyl)-1H-pyrazole hydrochloride (C8H10F3N3HCl) contains a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 241.64 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(Pyrrolidin-2-yl)-3-(trifluoromethyl)-1H-pyrazole hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10F3N3 HCl |
| Molecular Weight | 241.64 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Pyrrolidin Standards
- 1000018-40-5 3-pyrrolidin-1-yl-4-(methylsulphonyl)aniline 4-Methylsulfonyl-3-(pyrrolidin-1-yl)aniline (CAS 1000018-40-5)
- Ethyl 2-(pyrrolidin-1-yl)-4-(trifluoromethyl)thiazole-5-carboxylate (CAS 1000339-79-6)
- 2-[4-(Pyrrolidin-3-yloxy)phenyl]ethylamine (CAS 1000507-30-1)
- 4-(Pyrrolidin-3-yl)-1H-pyrazole (CAS 1000772-62-2)
- 1-(2-(Pyrrolidin-1-yl)ethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1000802-52-7)
- 1-(Pyrrolidin-1-ylsulfonyl)-4,4'-bipiperidine (CAS 1000958-63-3)
- 2-PYrrolidin-3-yl-1h-pyrrolo[2,3-b]pyridine dihydrochloride (CAS 1001069-32-4)
- (1-(Pyrrolidin-1-ylmethyl)cyclopropyl)methanamine dihydrochloride (CAS 1001345-81-8)
Recommended Standards
- Ethyl 3-(4-methyl-3,5-dioxo-2-(p-tolyl)-2,3,4,5-tetrahydro-1,2,4-triazin-6-yl)-1,2,4-oxadiazole-5-carboxylate (CAS 932974-35-1)
- 3-[(Dimethylamino)methyl]aniline (CAS 27958-77-6)
- Pentafluoro-N-methylaniline (CAS 1201-02-1)
- 3-bromo-5-isopropyl-1,2,4-oxadiazole (CAS 121562-07-0)
- Atorvastatin Impurity 55 (CAS 196085-84-4)
- 8-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-7-amine (CAS 89284-31-1)
- N-(2-Nitro-9H-fluoren-3-yl)acetamide (CAS 108621-27-8)
- 4-(2-Chloro-4-nitrostyryl)benzene-1-sulfonyl fluoride (CAS 21278-66-0)
- 2-{4-[5-(2,5-dimethoxyphenyl)-1H-pyrazol-3-yl]piperidin-1-yl}-3-nitropyridine (CAS 1026077-65-5)
- Semaglutide impurity 31 (CAS CATO-C4X-222631)
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