3-(3,5-Difluoro-biphenyl-2-ylmethyl)-1-methyl-piperazin-2-one CAS 1361111-85-4
| CAS No. | 1361111-85-4 |
| Molecular Formula | C18H18F2N2O |
| Molecular Weight | 316.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-(3,5-Difluoro-biphenyl-2-ylmethyl)-1-methyl-piperazin-2-one (CAS 1361111-85-4), molecular formula C18H18F2N2O and molecular weight 316.35 g/mol, is a CATO reference standard with documented purity and traceability.
3-(3,5-Difluoro-biphenyl-2-ylmethyl)-1-methyl-piperazin-2-one (C18H18F2N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H18F2N2O |
| Molecular Weight | 316.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- (3aR,3'aR,8aS,8'aS)-3a,3'a,8a,8'a-Tetrahydro-8H,8'H-2,2'-biindeno[1,2-d]oxazole (CAS 1354558-61-4)
- 3-(2-(Naphthalen-2-yloxy)ethyl)quinazolin-4(3H)-one (CAS 138841-14-2)
- 1-Methanesulfonyl-3-methylpiperidin-4-amine (CAS 1228453-26-6)
- 4-Fluoro-2-methoxy-5-nitropyridine (CAS 1935918-25-4)
- Thymidylyl-3-5-thymidine ammonium salt (CAS 1969-54-6)
- Ethyl 2-Pyrimidinecarboxylate (CAS 42839-08-7)
- (2,2-Dimethyl-1-propanethiolato)(triphenylphosphine)gold (CAS 1002113-78-1)
- Methyl 4-amino-2-(4-benzyl-1,4-diazepan-1-yl)thiazole-5-carboxylate (CAS 2108876-21-5)
- 2-(Cyanomethoxy)ethyl acetate (CAS 107886-27-1)
- 3-Bromo-6-chloroindazole (CAS 885521-34-6)
- N2-(tert-Butyl)-5-nitropyrimidine-2,4-diamine (CAS 1286698-57-4)
- Peptide Impurity 34 (CAS 21282-09-7)
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