4-Piperidin-3-yl-5-(4-trifluoromethyl-phenyl)-pyrimidin-2-ylamine CAS 1361112-72-2
| CAS No. | 1361112-72-2 |
| Molecular Formula | C16H17F3N4 |
| Molecular Weight | 322.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Piperidin-3-yl-5-(4-trifluoromethyl-phenyl)-pyrimidin-2-ylamine (CAS 1361112-72-2), a certified reference material (molecular formula C16H17F3N4, MW 322.33 g/mol) for analytical method development and quality control.
The molecular framework of 4-Piperidin-3-yl-5-(4-trifluoromethyl-phenyl)-pyrimidin-2-ylamine (C16H17F3N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H17F3N4 |
| Molecular Weight | 322.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Piperidin Standards
- 3-(6-(Piperidin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)benzamide (CAS 596824-07-6)
- 36257-55-3 2-[2-(Piperidin-1-ylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione MFCD08339556 (CAS 36257-55-3)
- 1-((4-(Piperidin-4-ylmethyl)phenyl)sulfonyl)piperidine (CAS 333987-64-7)
- N-(4-(Piperidin-1-yl)but-2-yn-1-yl)-4-(1H-pyrrol-1-yl)benzamide (CAS 1396568-40-3)
- 9-Benzyl-6-(2-(piperidin-1-yl)ethyl)-9H-purine (CAS 920503-17-9)
- [(1-Boc-piperidin-4-ylidene)methyl]boronic Acid Pinacol Ester (CAS 1425970-61-1)
- 3-(6-(Piperidin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)benzoic acid (CAS 821002-67-9)
- N-(2-(Piperidin-1-yl)ethyl)-7-(trifluoromethyl)quinolin-4-amine (CAS 289628-56-4)
Recommended Standards
- 4-(3-Fluorobenzoyl)-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326810-70-1)
- 3-[3-(Benzyloxy)phenyl]-2-fluorobenzoic acid (CAS 1381944-41-7)
- (E)-N,N-dimethyl-6-(3-((2-methylhydrazono)methyl)phenyl)-4-(trifluoromethyl)pyridin-2-amine (CAS 1311283-78-9)
- (R)-2-((tert-butoxycarbonyl)amino)-3-(7-fluoro-1H-indol-3-yl)propanoic acid (CAS 1384101-98-7)
- 2-Amino-N,3-diphenylpropanamide hydrochloride (CAS 857770-81-1)
- 4-(3,4-Dichlorophenyl)-2-(4-methylphenyl)-4-oxobutanoic acid (CAS 344282-29-7)
- N-(5,6-dimethyl-1-(2-methylbenzyl)-1H-benzo[d]imidazol-4-yl)-4-fluorobenzenesulfonamide (CAS 338954-62-4)
- 1-(5-Bromothiophen-2-yl)piperidine (CAS 840464-73-5)
- Ethyl 1-methyl-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 60442-66-2)
- Pralidoxime Chloride (CAS 51-15-0)
- 1-(2-(3,5-Dimethyl-1H-pyrazol-1-yl)ethyl)-3-(2-phenoxyethyl)urea (CAS 1396865-49-8)
- (E)-3-(5-Chloro-2,4-difluorophenyl)acrylic acid (CAS 2307843-32-7)
- 3-Hydroxypropyl hydrogen mesitylboronate (CAS 141522-24-9)
- Acetyl tetrapeptide-3 (CAS 827306-88-7)
Why CATO?
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