2-(6-(2-(Trifluoromethyl)benzyl)pyridin-2-yl)morpholine CAS 1361114-74-0
| CAS No. | 1361114-74-0 |
| Molecular Formula | C17H17F3N2O |
| Molecular Weight | 322.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(6-(2-(Trifluoromethyl)benzyl)pyridin-2-yl)morpholine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(6-(2-(Trifluoromethyl)benzyl)pyridin-2-yl)morpholine (CAS 1361114-74-0) is a high-purity analytical reference standard with the molecular formula C17H17F3N2O and a molecular weight of 322.32 g/mol.
The molecular framework of 2-(6-(2-(Trifluoromethyl)benzyl)pyridin-2-yl)morpholine (C17H17F3N2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C17H17F3N2O |
| Molecular Weight | 322.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 1-(4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl)piperidin-4-amine (CAS 1018125-23-9)
- 1-(6-(4-(Trifluoromethyl)phenyl)pyridazin-3-yl)piperidin-3-amine (CAS 919496-28-9)
- 4-Methyl-5-{[2-(trifluoromethyl)phenyl]methanesulfonyl}-1,2,3-thiadiazole (CAS 400087-44-7)
- 3-Phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxamide (CAS 478260-63-8)
- 4-((3-(Trifluoromethyl)phenyl)sulfonyl)piperazine-1-carbaldehyde (CAS 866152-66-1)
- N-(3-(trifluoromethyl)benzyl)-1,4-dihydro-2H-benzo[d][1,3]thiazin-2-imine (CAS 400077-86-3)
- (2E)-3-(3-{[4-(trifluoromethyl)phenyl]methoxy}phenyl)prop-2-enoic acid (CAS 866151-64-6)
- Bis(4-(trifluoromethyl)phenyl)sulfane (CAS 90141-51-8)
Recommended Standards
- N-(1-(2,2-Dimethyl-6-nitro-2H-chromen-4-yl)pyridin-2(1H)-ylidene)cyanamide (CAS 135809-60-8)
- N-(2-((2-(1H-Imidazol-1-yl)pyrimidin-5-yl)amino)-2-oxoethyl)benzamide (CAS 1421443-99-3)
- 1-(4-Nitrobenzyl)-N-phenyl-1H-imidazole-4-carboxamide (CAS 1351848-60-6)
- N'-(9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-2,9-dihydro-1H-purin-6-yl)-N,N-dimethylformimidamide (CAS 146196-17-0)
- N-Allyl-6-chloro-5-(1H-pyrrol-1-yl)pyrimidin-4-amine (CAS 1707394-14-6)
- (4R,5R,6S,7R)-7-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)-4,5,6,8-tetrahydroxy-2-oxooctanoic acid (CAS 129476-66-0)
- 2-Amino-4,6-dimethoxypyrimidin-5-ol (CAS 267224-18-0)
- 1,4-Dibutylbenzene (CAS 1571-86-4)
- Moexipril-d5 (CAS 1356929-49-1)
- 3,5-Dibromo-4-methylbenzamide (CAS 289039-51-6)
- 5-fluoro-2-phenyl-4-(trifluoromethyl)-1,3-oxazole (CAS 70276-69-6)
- Methyl 2-bromo-5-cyclopropylbenzoate (CAS 702640-96-8)
- N-(2,3-Dimethylquinoxalin-6-yl)-4-methoxybenzene-1-sulfonamide (CAS 672950-12-8)
- Peptide Impurity 41 (CAS CATO-CPTD788841)
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