5-Ethyl-1-(phenethoxymethyl)-6-(phenylthio)pyrimidine-2,4(1H,3H)-dione CAS 136160-44-6
| CAS No. | 136160-44-6 |
| Molecular Formula | C21H22N2O3S |
| Molecular Weight | 382.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Ethyl-1-(phenethoxymethyl)-6-(phenylthio)pyrimidine-2,4(1H,3H)-dione is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Ethyl-1-(phenethoxymethyl)-6-(phenylthio)pyrimidine-2,4(1H,3H)-dione (CAS 136160-44-6), a certified reference material (molecular formula C21H22N2O3S, MW 382.48 g/mol) for analytical method development and quality control.
The molecular framework of 5-Ethyl-1-(phenethoxymethyl)-6-(phenylthio)pyrimidine-2,4(1H,3H)-dione (C21H22N2O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H22N2O3S |
| Molecular Weight | 382.48 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
Recommended Standards
- 1-((Benzyloxy)methyl)-5-isopropyl-6-(phenylthio)pyrimidine-2,4(1H,3H)-dione (CAS 136160-34-4)
- 2-(1-((2-(Methylamino)pyrimidin-5-yl)methyl)piperidin-3-yl)-6-(thiophen-2-yl)pyrimidin-4(3H)-one (CAS 1381289-58-2)
- 2-[(5-{[(4-Methylphenyl)amino]methyl}-4-phenyl-4H-1,2,4-triazol-3-yl)thio]propanohydrazide (CAS 1306738-81-7)
- 1-(1-(3-(Thiophen-3-yl)-1,2,4-oxadiazol-5-yl)cyclohexyl)-3-(o-tolyl)urea (CAS 1396635-36-1)
- 1-Piperazinecarboxylic acid, 4-(4-bromo-3-ethoxybenzoyl)-, 1,1-dimethylethyl ester (CAS 1352621-05-6)
- 3-Hydroxy-1-(isopropylthio)cyclobutane-1-carboxylic acid (CAS 1465990-53-7)
- Hexamethylenediaminetetra(methylenephosphonic acid) xpotassium salt (CAS 38820-59-6)
- 19628-76-3 3, 4-nitroso- 3,5-Dimethyl-4-nitrosophenol NSC-38029 NSC38029 Phenol,5-dimethyl-4-nitroso- (CAS 19628-76-3)
- 4-Isopropylpyrimidin-5-amine (CAS 1368846-71-2)
- (-)-(1S,2S,5S)-2-Hydroxy-3-pinanone (CAS 1845-25-6)
- 17B(H)-22,29,30-Trisnorhopane (CAS 51271-94-4)
- Methyl 2,4-dichloro-5-(difluoromethoxy)benzoate (CAS 1806349-28-9)
- 5-Amino-4-fluoro-2-nitrobenzoic acid (CAS 53994-61-9)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com