2-(2,5-Dichlorophenyl)pyrimidine-5-carboxylic acid CAS 1361683-25-1
| CAS No. | 1361683-25-1 |
| Molecular Formula | C11H6Cl2N2O2 |
| Molecular Weight | 269.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2,5-Dichlorophenyl)pyrimidine-5-carboxylic acid.
2-(2,5-Dichlorophenyl)pyrimidine-5-carboxylic acid (CAS 1361683-25-1), molecular formula C11H6Cl2N2O2 and molecular weight 269.08 g/mol, is a CATO reference standard with documented purity and traceability.
2-(2,5-Dichlorophenyl)pyrimidine-5-carboxylic acid (C11H6Cl2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H6Cl2N2O2 |
| Molecular Weight | 269.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorophenyl Standards
- 6-(3,4-Dichlorophenyl)pyrimidine-4-carboxylic acid (CAS 1207723-55-4)
- 2-(2,6-Dichlorophenyl)pyrimidine-5-carboxylic acid (CAS 1267587-09-6)
- 2-(2,4-Dichlorophenyl)pyrimidine-5-carboxylic acid (CAS 928713-28-4)
- 2-(3,4-Dichlorophenyl)pyrimidine-5-carboxylic acid (CAS 928713-43-3)
- 2-(3,5-Dichlorophenyl)pyrimidine-5-carboxylic acid (CAS 954227-41-9)
- Ethyl 2-(2,3-dichlorophenyl)-2,2-difluoroacetate (CAS 1199773-04-0)
- Ethyl 2-(2,5-dichlorophenyl)-2,2-difluoroacetate (CAS 1215206-21-5)
- Ethyl 2-(3,4-dichlorophenyl)-2,2-difluoroacetate (CAS 56177-76-5)
Recommended Standards
- 2-(2-(Iodomethyl)pyrrolidin-1-yl)acetic acid (CAS 1353979-98-2)
- (4-(((tert-Butoxycarbonyl)amino)methyl)-3-fluorophenyl)boronic acid (CAS 1374451-80-5)
- 2-(3-(Iodomethyl)pyrrolidin-1-yl)acetic acid (CAS 1353978-46-7)
- 3-iodo-8-methylquinoline (CAS 1424245-96-4)
- (1-(2-Fluorobenzyl)-1h-1,2,3-triazol-4-yl)methanamine (CAS 1249550-65-9)
- 1-Chloro-4-(isopropylsulfonyl)butane (CAS 128147-28-4)
- 6-iodobenzofuran-3-one (CAS 1199782-68-7)
- 2-Bromo-4-chloro-6-methoxybenzo[d]thiazole (CAS 1464091-50-6)
- 1H-Indazole-3-carboxamide (CAS 90004-04-9)
- 4-(4-Isopropylphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine (CAS 303021-39-8)
- 1-(m-Tolyl)imidazolidin-2-one (CAS 14088-94-9)
- 5-(3-Isopropyl-1,2,4-oxadiazol-5-yl)-4-methylthiazol-2-amine (CAS 1119416-02-2)
- (3-Chloro-5-fluorophenyl)(4-(piperidin-1-ylmethyl)phenyl)methanone (CAS 898775-47-8)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
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