4-(Aminomethyl)-6-(difluoromethyl)-2-(trifluoromethyl)pyridine-3-sulfonyl chloride CAS 1361702-12-6
| CAS No. | 1361702-12-6 |
| Molecular Formula | C8H6ClF5N2O2S |
| Molecular Weight | 324.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Aminomethyl)-6-(difluoromethyl)-2-(trifluoromethyl)pyridine-3-sulfonyl chloride.
CATO supplies 4-(Aminomethyl)-6-(difluoromethyl)-2-(trifluoromethyl)pyridine-3-sulfonyl chloride (CAS 1361702-12-6), a certified reference material (molecular formula C8H6ClF5N2O2S, MW 324.66 g/mol) for analytical method development and quality control.
4-(Aminomethyl)-6-(difluoromethyl)-2-(trifluoromethyl)pyridine-3-sulfonyl chloride (C8H6ClF5N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(Aminomethyl)-6-(difluoromethyl)-2-(trifluoromethyl)pyridine-3-sulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF5N2O2S |
| Molecular Weight | 324.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Aminomethyl Standards
- 4-(Aminomethyl)-5-(difluoromethyl)-2-(trifluoromethyl)pyridine-3-sulfonyl chloride (CAS 1361468-12-3)
- 2-(Aminomethyl)-3-(difluoromethyl)-5-(trifluoromethyl)pyridine-6-sulfonyl chloride (CAS 1361703-11-8)
- 4-(Aminomethyl)-3-(difluoromethyl)-6-(trifluoromethyl)pyridine-2-sulfonyl chloride (CAS 1361703-48-1)
- 2-(Aminomethyl)-3-(difluoromethyl)-6-(trifluoromethyl)pyridine-5-sulfonyl chloride (CAS 1361734-41-9)
- 2-(Aminomethyl)-4-(difluoromethyl)-3-(trifluoromethyl)pyridine-6-sulfonyl chloride (CAS 1361785-11-6)
- 2-(Aminomethyl)-4-(difluoromethyl)-3-(trifluoromethyl)pyridine-5-sulfonyl chloride (CAS 1361797-47-8)
- 2-(Aminomethyl)-5-(difluoromethyl)-6-(trifluoromethyl)pyridine-3-sulfonyl chloride (CAS 1361798-05-1)
- 2-(Aminomethyl)-5-(difluoromethyl)-3-(trifluoromethyl)pyridine-4-sulfonyl chloride (CAS 1361815-51-1)
Recommended Standards
- 2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 865352-01-8)
- 3-bromo-6-chloro-1-tetrahydropyran-2-yl-pyrazolo[4,3-c]pyridine (CAS 1416712-71-4)
- 4'-Chloro-2,4-bis(trifluoromethyl)-1,1'-biphenyl (CAS 1333319-59-7)
- ethyl 8-bromo-4-chloroquinoline-3-carboxylate (CAS 206258-97-1)
- Benzyl 2,7-diazaspiro[3.5]nonane-2-carboxylate hydrochloride (CAS 1227381-91-0)
- N1-(5-bromopyridin-2-yl)pentane-1,5-diamine (CAS 199522-81-1)
- 2-Methyl-6-(trifluoromethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine (CAS 1196156-48-5)
- N-(4-(2-chlorophenyl)thiazol-2-yl)-2-((2,6-dichlorophenyl)thio)acetamide (CAS 338957-66-7)
- 1-[2-Methyl-6-(trifluoromethyl)pyrimidin-4-yl]-N-[(thiophen-2-yl)methyl]piperidine-4-carboxamide (CAS 1775322-69-4)
- Ethyl 4-(3,4-diacetyl-2,5-dimethyl-1H-pyrrol-1-yl)benzoate (CAS 214221-37-1)
- ISopropyl (3s)-2-(4-fluorophenyl)-3-pyrrolidinecarboxylate oxalate (CAS 1214623-00-3)
- 4-Chloro-N-{[4-(prop-2-en-1-yl)-5-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-4H-1,2,4-triazol-3-yl]methyl}benzene-1-sulfonamide (CAS 338422-25-6)
- (R)-3-(2-methoxyphenoxy)butanoic acid (CAS 1416445-13-0)
- Insulin Degludec Impurity 27 (CAS CATO-C4X-215727)
Why CATO?
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