2-(Chloromethyl)-5-(difluoromethyl)-3-methylpyridine-6-methanol CAS 1361752-27-3
| CAS No. | 1361752-27-3 |
| Molecular Formula | C9H10ClF2NO |
| Molecular Weight | 221.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Chloromethyl)-5-(difluoromethyl)-3-methylpyridine-6-methanol (CAS 1361752-27-3), molecular formula C9H10ClF2NO and molecular weight 221.63 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C9H10ClF2NO, 2-(Chloromethyl)-5-(difluoromethyl)-3-methylpyridine-6-methanol contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 221.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(Chloromethyl)-5-(difluoromethyl)-3-methylpyridine-6-methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H10ClF2NO |
| Molecular Weight | 221.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- 2-(Chloromethyl)-6-(difluoromethyl)-3-methylpyridine-5-methanol (CAS 1361869-16-0)
- 2-(Chloromethyl)-3-(difluoromethyl)-4-methylpyridine-6-methanol (CAS 1361879-73-3)
- 2-(Chloromethyl)-6-(difluoromethyl)-3-methylpyridine-4-methanol (CAS 1361879-86-8)
- 2-(Chloromethyl)-4-(difluoromethyl)-3-methylpyridine-6-methanol (CAS 1361901-17-8)
- 2-(Chloromethyl)-3-(difluoromethyl)-5-methylpyridine-6-methanol (CAS 1361917-17-0)
- 2-(Chloromethyl)-3-(difluoromethyl)-4-methoxy-6-methylpyridine (CAS 1805440-32-7)
- 2-(Chloromethyl)-4-(difluoromethyl)-3-methoxy-6-methylpyridine (CAS 1805440-51-0)
- 2-(Chloromethyl)-5-(difluoromethyl)-3-methoxy-4-methylpyridine (CAS 1805440-73-6)
Recommended Standards
- (R)-1-(5-Chloro-2-(difluoromethoxy)phenyl)ethan-1-amine (CAS 1344934-50-4)
- (S)-1-(5-Chloro-2-(difluoromethoxy)phenyl)ethan-1-amine (CAS 1344908-43-5)
- (1S,2S)-1-Amino-1-(4-chloro-2,5-difluorophenyl)propan-2-ol (CAS 1270186-08-7)
- 1-(3-Chloro-4-(difluoromethoxy)phenyl)-N-methylmethanamine (CAS 1250155-09-9)
- 7-Ethynylpyrazolo[1,5-a]pyridine (CAS 319432-33-2)
- Azelastine Impurity 5 (CAS 88061-65-8)
- 2-Methylaminothioacetamide HCl (CAS 118020-65-8)
- Ethyl 5-(4-bromophenyl)-1,3,4-oxadiazole-2-carboxylate (CAS 931760-32-6)
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- N-(2,2-dimethylcyclopentyl)thietan-3-amine (CAS 1862888-44-5)
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