2-(Aminomethyl)-5-(difluoromethyl)-6-methoxypyridine-3-carboxaldehyde CAS 1361772-16-8
| CAS No. | 1361772-16-8 |
| Molecular Formula | C9H10F2N2O2 |
| Molecular Weight | 216.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Aminomethyl)-5-(difluoromethyl)-6-methoxypyridine-3-carboxaldehyde.
2-(Aminomethyl)-5-(difluoromethyl)-6-methoxypyridine-3-carboxaldehyde (CAS 1361772-16-8) is a high-purity analytical reference standard with the molecular formula C9H10F2N2O2 and a molecular weight of 216.18 g/mol.
The molecular framework of 2-(Aminomethyl)-5-(difluoromethyl)-6-methoxypyridine-3-carboxaldehyde (C9H10F2N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H10F2N2O2 |
| Molecular Weight | 216.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Aminomethyl Standards
- 2-(Aminomethyl)-4-(difluoromethyl)-5-methoxypyridine-3-carboxaldehyde (CAS 1361469-77-3)
- 2-(Aminomethyl)-5-(difluoromethyl)-3-methoxypyridine-4-carboxaldehyde (CAS 1361702-13-7)
- 4-(Aminomethyl)-3-(difluoromethyl)-5-methoxypicolinaldehyde (CAS 1361732-32-2)
- 2-(Aminomethyl)-3-(difluoromethyl)-6-methoxypyridine-5-carboxaldehyde (CAS 1361756-76-4)
- 2-(Aminomethyl)-3-(difluoromethyl)-4-methoxypyridine-6-carboxaldehyde (CAS 1361772-08-8)
- 2-(Aminomethyl)-6-(difluoromethyl)-4-methoxypyridine-3-carboxaldehyde (CAS 1361781-59-0)
- 2-(Aminomethyl)-5-(difluoromethyl)-3-methoxypyridine-6-carboxaldehyde (CAS 1361798-89-1)
- 2-(Aminomethyl)-3-(difluoromethyl)-5-methoxypyridine-6-carboxaldehyde (CAS 1361813-42-4)
Recommended Standards
- 2-(Aminomethyl)-3-(difluoromethyl)-6-methoxypyridine-4-carboxaldehyde (CAS 1361819-58-0)
- 2-(Aminomethyl)-6-(difluoromethyl)-3-methoxypyridine-4-carboxaldehyde (CAS 1361819-87-5)
- Methyl 2-(3-(difluoromethoxy)phenyl)acetate (CAS 1354757-93-9)
- 2-(Aminomethyl)-6-(difluoromethyl)-5-methoxypyridine-3-carboxaldehyde (CAS 1361843-74-4)
- 1-Chloro-6,6-dimethyl-3-(methylthio)-6,7-dihydrobenzo[c]thiophen-4(5H)-one (CAS 175202-90-1)
- N-(2-Bromo-4-(trifluoromethyl)-phenyl)piperidin-1-amine 1551146-16-7 (CAS 1551146-16-7)
- 5,7-dihydro-4H-spiro[1,3-benzothiazole-6,1’-cyclohexane]-2-amine (CAS 188051-12-9)
- 5-(2-Bromoethyl)-2,2-dimethyl-1,3-dioxane (CAS 97845-58-4)
- Ethyl 2-(4-(2-chlorophenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetate (CAS 861205-99-4)
- 2-(2-Methoxyphenoxy)-1-(tetrahydrofuran-3-yl)ethan-1-one (CAS 1920937-56-9)
- 2,6-Di-tert-butyl-4-[(ethylamino)methyl]phenol hydrochloride (CAS 141545-89-3)
- (3-Bromo-4-methylphenyl)hydrazine hydrochloride (CAS 112627-04-0)
- 2-{[4-(4-methoxyphenyl)-5-methyl-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 743452-47-3)
- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
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