2-(Aminomethyl)-3-(difluoromethyl)-6-(trifluoromethyl)pyridine-5-acetic acid CAS 1361821-59-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1361821-59-1
Molecular FormulaC10H9F5N2O2
Molecular Weight284.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Aminomethyl)-3-(difluoromethyl)-6-(trifluoromethyl)pyridine-5-acetic acid CAS 1361821-59-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 284.18 g/mol gives 2-(Aminomethyl)-3-(difluoromethyl)-6-(trifluoromethyl)pyridine-5-acetic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-(Aminomethyl)-3-(difluoromethyl)-6-(trifluoromethyl)pyridine-5-acetic acid (CAS 1361821-59-1), a certified reference material (molecular formula C10H9F5N2O2, MW 284.18 g/mol) for analytical method development and quality control.

The molecular framework of 2-(Aminomethyl)-3-(difluoromethyl)-6-(trifluoromethyl)pyridine-5-acetic acid (C10H9F5N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H9F5N2O2
Molecular Weight284.18 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms2

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