3-Bromo-5-(trifluoromethoxy)pyridin-2-ol CAS 1361837-97-9
| CAS No. | 1361837-97-9 |
| Molecular Formula | C6H3BrF3NO2 |
| Molecular Weight | 257.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 257.99 g/mol gives 3-Bromo-5-(trifluoromethoxy)pyridin-2-ol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Bromo-5-(trifluoromethoxy)pyridin-2-ol (CAS 1361837-97-9), a certified reference material (molecular formula C6H3BrF3NO2, MW 257.99 g/mol) for analytical method development and quality control.
The molecular framework of 3-Bromo-5-(trifluoromethoxy)pyridin-2-ol (C6H3BrF3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Bromo-5-(trifluoromethoxy)pyridin-2-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H3BrF3NO2 |
| Molecular Weight | 257.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 3-Bromo-6-(trifluoromethyl)pyridine-2,4-diol (CAS 1214359-51-9)
- 1-bromo-2-(bromomethyl)-3,3-dimethylbutane (CAS 14924-49-3)
- 2-Bromo-6-fluoro-4-(trifluoromethyl)aniline (CAS 1034325-63-7)
- 4-Bromo-2-fluoro-5-(trifluoromethyl)aniline (CAS 104460-70-0)
- 4-Bromo-3-fluoro-2-(trifluoromethyl)aniline (CAS 1092460-59-7)
- 6-Bromo-2-fluoro-3-(trifluoromethyl)aniline (CAS 1217303-26-8)
- 3-Bromo-4-fluoro-5-(trifluoromethyl)aniline (CAS 1233026-11-3)
- 4-Bromo-2,3,5,6-tetrafluoro-N-methylaniline (CAS 1233506-07-4)
Recommended Standards
- 2,4,6-Trifluoroiodobenzene (CAS 41860-63-3)
- 1,1-Dibromoheptane (CAS 59104-79-9)
- 2,3,5-Trifluoroiodobenzene (CAS 622379-51-5)
- 1,5-Dibromo-3,3-dimethylpentane (CAS 37746-17-1)
- Tris[tris(3,5-bis(trifluoromethyl)phenyl)phosphine] palladium(0) (CAS 1130784-80-3)
- 1,3,5-Trichloro-2-Nitrobenzene (CAS 18708-70-8)
- (2-Chloro-6-(trifluoromethyl)pyridin-4-yl)methanamine (CAS 1060810-25-4)
- Alpha-Boswellic Acid (CAS 471-66-9)
- 2-(4-Fluorobenzyl)oxazole-4-carboxylic Acid (CAS 500367-21-5)
- Tert-butyl (R)-1-oxo-2,6-diazaspiro[4.5]Decane-6-carboxylate (CAS 2183458-12-8)
- (3',5'-Dichloro-[1,1'-biphenyl]-4-yl)methanaminehydrochloride (CAS 518357-39-6)
- 3-Isopropyl-1H-indazol-5-amine (CAS 1401084-17-0)
- 5-Amino-N-(2,2-difluoroethyl)-4-fluoro-2-methylbenzamide (CAS 1877578-00-1)
- Semaglutide impurity 41 (CAS CATO-C4X-222641)
Why CATO?
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