2-(Trifluoromethoxy)pyridin-4-ol CAS 1361880-86-5
| CAS No. | 1361880-86-5 |
| Molecular Formula | C6H4F3NO2 |
| Molecular Weight | 179.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C6H4F3NO2, 2-(Trifluoromethoxy)pyridin-4-ol contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 179.10 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(Trifluoromethoxy)pyridin-4-ol (CAS 1361880-86-5), molecular formula C6H4F3NO2 and molecular weight 179.10 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Trifluoromethoxy)pyridin-4-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4F3NO2 |
| Molecular Weight | 179.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethoxy Standards
- 5-(Trifluoromethoxy)pyridin-2(1H)-one (CAS 1052722-33-4)
- 6-(Trifluoromethoxy)pyrazin-2-amine (CAS 1261576-51-5)
- 5-(Trifluoromethoxy)pyrazin-2-amine (CAS 1261884-22-3)
- 2-(Trifluoromethoxy)pyridin-3-ol (CAS 1361836-59-0)
- 2-(cis-3-(Trifluoromethoxy)cyclobutyl)acetonitrile (CAS 2489409-54-1)
- 2-(Trifluoromethoxy)pyridin-3-amine (CAS 1221171-94-3)
- 2-(Trifluoromethoxy)pyridin-4-amine (CAS 1221172-01-5)
- 6-(Trifluoromethoxy)pyridin-3-amine (CAS 135900-33-3)
Recommended Standards
- 3-(Trifluoromethyl)-1H-pyrrole-2-carboxylic acid (CAS 1367870-78-7)
- 5-Methyl-4-nitroso-3-(trifluoromethyl)-1H-pyrazole (CAS 1291099-86-9)
- 1-(2,2,2-Trifluoroethyl)-1H-1,2,3-triazole-4-carbaldehyde (CAS 1393568-30-3)
- 5-(Trifluoromethyl)pyrazole-3-carboxamide (CAS 1276541-94-6)
- N-(3-Bromo-4-chlorophenyl)acetamide (CAS 22459-83-2)
- Glyceryl trinonate (CAS 126-53-4)
- 3-(Methylthio)-1H-pyrazole (CAS 774157-81-2)
- 4-(2-Oxo-1,2,3,4-tetrahydroquinolin-1-yl)butanoic acid (CAS 933696-07-2)
- 4-(4-Chlorophenoxy)butane-1-sulfonyl chloride (CAS 1339813-92-1)
- 1-(Furan-2-yl)-N,N,N-trimethylmethanaminium bromide (CAS 73664-18-3)
- (3-Chlorophenyl)(2-iodophenyl)methanone (CAS 890098-14-3)
- 2-((3-Chlorophenyl)sulfonyl)-N-methyl-N-phenylacetamide (CAS 339108-28-0)
- Methyl 2-Bromooctanoate (CAS 5445-22-7)
- Insulin Degludec Impurity 19 (CAS CATO-C4X-215719)
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