2-(4-(Chloromethyl)-5-(difluoromethyl)-6-methylpyridin-3-yl)acetonitrile CAS 1361886-17-0
| CAS No. | 1361886-17-0 |
| Molecular Formula | C10H9ClF2N2 |
| Molecular Weight | 230.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-(4-(Chloromethyl)-5-(difluoromethyl)-6-methylpyridin-3-yl)acetonitrile (CAS 1361886-17-0) is a high-purity analytical reference standard with the molecular formula C10H9ClF2N2 and a molecular weight of 230.64 g/mol.
2-(4-(Chloromethyl)-5-(difluoromethyl)-6-methylpyridin-3-yl)acetonitrile (C10H9ClF2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9ClF2N2 |
| Molecular Weight | 230.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloromethyl Standards
- 2-(Chloromethyl)-3-(difluoromethyl)-5-methylpyridine-4-acetonitrile (CAS 1361499-86-6)
- 2-(Chloromethyl)-6-(difluoromethyl)-4-methylpyridine-3-acetonitrile (CAS 1361695-34-2)
- 2-(Chloromethyl)-3-(difluoromethyl)-4-methylpyridine-5-acetonitrile (CAS 1361699-35-5)
- 2-(Chloromethyl)-5-(difluoromethyl)-3-methylpyridine-4-acetonitrile (CAS 1361751-86-1)
- 2-(Chloromethyl)-6-(difluoromethyl)-5-methylpyridine-3-acetonitrile (CAS 1361751-92-9)
- 2-(Chloromethyl)-4-(difluoromethyl)-3-methylpyridine-6-acetonitrile (CAS 1361800-32-9)
- 2-(Chloromethyl)-5-(difluoromethyl)-6-methylpyridine-3-acetonitrile (CAS 1361800-43-2)
- 2-(Chloromethyl)-5-(difluoromethyl)-4-methylpyridine-3-acetonitrile (CAS 1361808-71-0)
Recommended Standards
- 2-(Chloromethyl)-6-(difluoromethyl)-3-methylpyridine-4-acetonitrile (CAS 1361868-94-1)
- 3-(3-Chloro-4-methoxyphenyl)-3-hydroxypropanoic acid (CAS 1468593-14-7)
- 2-(Chloromethyl)-3-(difluoromethyl)-6-methylpyridine-5-acetonitrile (CAS 1361868-89-4)
- Methyl 2-(4-chloro-3-methoxyphenyl)-2-hydroxyacetate (CAS 1503943-70-1)
- (S)-1-(2,5-dimethoxyphenyl)-2-methoxyethan-1-amine (CAS 1270095-76-5)
- 2-((3-Chloropyrazin-2-yl)amino)-2-phenylethan-1-ol (CAS 1492628-35-9)
- 2-((4-Methyl-4h-1,2,4-triazol-3-yl)thio)-1-(1,2,5-trimethyl-1h-pyrrol-3-yl)ethan-1-one (CAS 849055-92-1)
- tert-Butyl (4-methylthiophen-3-yl)carbamate (CAS 1097629-78-1)
- 2,3,4-Tri-O-acetyl-1-cyano-a-D-xylopyranosyl bromide (CAS 83497-43-2)
- Palbociclib Impurity 11 (CAS CATO-C4X-112511)
- N-(3-aminophenyl)-2-(4-methoxyphenyl)acetamide (CAS 1016766-95-2)
- 4-azido-1-tert-butylpiperidine (CAS 1258956-25-0)
- Flubendazole EP Impurity F (CAS 132119-20-1)
- Protein Kinase C? Peptide Substrate (CAS 120253-69-2)
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