2,3-Dichloro-2'-difluoromethoxy-5'-fluoro-biphenyl CAS 1361890-43-8
| CAS No. | 1361890-43-8 |
| Molecular Formula | C13H7Cl2F3O |
| Molecular Weight | 307.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,3-Dichloro-2'-difluoromethoxy-5'-fluoro-biphenyl (CAS 1361890-43-8) is a high-purity analytical reference standard with the molecular formula C13H7Cl2F3O and a molecular weight of 307.10 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2,3-Dichloro-2'-difluoromethoxy-5'-fluoro-biphenyl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 307.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H7Cl2F3O |
| Molecular Weight | 307.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
Related Dichloro Standards
- Ethyl 4-(2,6-Dichloro-3-fluorophenyl)-2,4-dioxobutanoate (CAS 1041553-00-7)
- 2',5'-Dichloro-3-(difluoromethoxy)-2-fluoro-1,1'-biphenyl (CAS 1361477-80-6)
- 2,4-Dichloro-4'-(difluoromethoxy)-3'-fluoro-1,1'-biphenyl (CAS 1361715-81-2)
- 2',6'-Dichloro-2-(difluoromethoxy)-5-fluoro-1,1'-biphenyl (CAS 1361716-22-4)
- 2,4-Dichloro-2'-(difluoromethoxy)-4'-fluoro-1,1'-biphenyl (CAS 1361726-08-0)
- 2,3-Dichloro-2'-(difluoromethoxy)-6'-fluoro-1,1'-biphenyl (CAS 1361745-28-9)
- 2',5'-Dichloro-4-(difluoromethoxy)-2-fluoro-1,1'-biphenyl (CAS 1361751-24-7)
- 2,4-Dichloro-4'-(difluoromethoxy)-2'-fluoro-1,1'-biphenyl (CAS 1361765-52-7)
Recommended Standards
- 2,3-Dichloro-3'-difluoromethoxy-2'-fluoro-biphenyl (CAS 1361801-23-1)
- 5-Bromo-4-(2,2-dimethoxy)ethyl-2-hydroxy-3-nitropyridine (CAS 1427504-38-8)
- 3-(5-Bromofuran-2-yl)-2-hydroxy-4H-chromen-4-one (CAS 1708037-46-0)
- 2′-Bromo-2′-deoxyuridine (CAS 4753-02-0)
- N-(1-Benzyl-5,6-dimethyl-1H-1,3-benzodiazol-4-yl)-3,5-dichlorobenzene-1-sulfonamide (CAS 338410-81-4)
- 1-(Cyclohexylmethoxy)-4-iodobenzene (CAS 877603-51-5)
- 1-(Pyrrolidin-1-ylmethyl)-6-azaspiro[2.5]Octane (CAS 1339519-58-2)
- (E)-N-[(6-bromo-2H-1,3-benzodioxol-5-yl)methylidene]hydroxylamine 10P-088 65417-74-5 (CAS 65417-74-5)
- (3-((2-Chloro-5-(trifluoromethyl)phenoxy)methyl)phenyl)boronic acid (CAS 871126-25-9)
- (2E)-2-[(Thiophen-2-yl)methylidene]-2,3,4,9-tetrahydro-1H-carbazol-1-one (CAS 366785-69-5)
- (6-Chloro-4-(difluoromethyl)-5-methylpyridin-2-yl)methanol (CAS 1806872-04-7)
- 4-(Thiophen-2-yl)-1H-pyrrole-3-carbonitrile (CAS 87388-71-4)
- 5-[(4-Methoxyphenyl)methyl]-2-[(1H-1,2,4-triazol-1-yl)methyl]pyrimidine-4,6-diamine (CAS 338965-25-6)
- Insulin Degludec Impurity 20 (CAS CATO-C4X-215720)
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