Fmoc-n-methyl-dl-leucine CAS 1362858-89-6
| CAS No. | 1362858-89-6 |
| Molecular Formula | C22H25NO4 |
| Molecular Weight | 367.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Fmoc-n-methyl-dl-leucine (C22H25NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Fmoc-n-methyl-dl-leucine (CAS 1362858-89-6), molecular formula C22H25NO4 and molecular weight 367.44 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H25NO4 |
| Molecular Weight | 367.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related Fmoc Standards
- (R)-2-[(Fmoc-amino)methyl]-4-methylpentanoic Acid (CAS 1018899-99-4)
- N-Fmoc-iminodiacetic acid (CAS 112918-82-8)
- Fmoc-L-b-methylisoleucine (CAS 1227750-73-3)
- Fmoc-N-Methyl-D-Isoleucine (CAS 1301706-63-7)
- Fmoc-D-b-methylisoleucine (CAS 1310680-40-0)
- Fmoc-N-Methyl-D-Allo-Isoleucine (CAS 1356090-81-7)
- Fmoc-t-butyl-L-alanine (CAS 139551-74-9)
- (R)-2-(Fmoc-amino)heptanoic acid (CAS 1629051-80-4)
Recommended Standards
- (4-((4-Fluorophenyl)amino)quinolin-3-yl)(thiomorpholino)methanone (CAS 1359224-41-1)
- 3-{[(9H-fluoren-9-ylmethoxy)carbonyl](2-methylpropyl)amino}propanoic acid (CAS 1393817-23-6)
- (4-((2-Fluorophenyl)amino)quinolin-3-yl)(thiomorpholino)methanone (CAS 1357782-88-7)
- Methyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-leucinate (CAS 139551-80-7)
- 2,3-Dibromodiphenyl ether (CAS 446254-14-4)
- 3-(4-Bromophenyl)-6-chloropyridazine (CAS 66548-50-3)
- Ethyl 3-Oxotetrahydrothiopyran-2-carboxylate (CAS 58509-73-2)
- N-(3,4-Dimethylphenyl)-2-((4-phenyl-1H-imidazol-2-yl)thio)propanamide (CAS 332101-64-1)
- 3-Fluoro-4'-methyl-[1,1'-biphenyl]-2-carboxylic acid (CAS 1261926-74-2)
- 5-((3-Fluorophenyl)ethynyl)picolinic acid (CAS 1403771-21-0)
- 5,10,15,20-Tetrakis-(4-aminophenyl)-porphyrin-Mn-(II) (CAS 71547-21-2)
- BRL 54443 (maleate) (CAS 1197333-54-2)
- tert-Butyl N-{2-azaspiro[3.5]nonan-7-yl}carbamate (CAS 1434142-07-0)
- Semaglutide impurity 01 (CAS 1998701-31-7)
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