Methyl (2S,3S)-2-amino-4,4-difluoro-3-hydroxy-3-methylbutanoate CAS 1363373-73-2
| CAS No. | 1363373-73-2 |
| Molecular Formula | C6H11F2NO3 |
| Molecular Weight | 183.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl (2S,3S)-2-amino-4,4-difluoro-3-hydroxy-3-methylbutanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Methyl (2S,3S)-2-amino-4,4-difluoro-3-hydroxy-3-methylbutanoate (CAS 1363373-73-2), a certified reference material (molecular formula C6H11F2NO3, MW 183.15 g/mol) for analytical method development and quality control.
Methyl (2S,3S)-2-amino-4,4-difluoro-3-hydroxy-3-methylbutanoate (C6H11F2NO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H11F2NO3 |
| Molecular Weight | 183.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 6,8-Difluoro-3,4-dihydroisoquinolin-1(2H)-one (CAS 1352398-60-7)
- 3-(2,6-Difluorophenoxy)propanenitrile (CAS 1379161-50-8)
- 6,7-Difluoro-3,4-dihydroisoquinolin-1(2H)-one (CAS 1352393-61-3)
- 2-Hydrazinyl-4-(trifluoromethyl)-1,3-thiazole (CAS 137929-07-8)
- 4-Allyl-5-{[3-(trifluoromethyl)phenoxy]methyl}-4H-1,2,4-triazole-3-thiol (CAS 862652-27-5)
- 4-((3,6-Diphenyl-1,2,4-triazin-5-yl)oxy)benzonitrile (CAS 339013-23-9)
- 2,5-Dimethyl-6,7-dihydro-5H-cyclopenta[b]pyrazine (CAS 38917-61-2)
- Deferoxamine hydrochloride (CAS 1950-39-6)
- 4-Bromo-7-methoxyquinoline-6-carbonitrile (CAS 2089326-76-9)
- 1,3-Dibromo-2,5-difluoro-4-(trifluoromethoxy)benzene (CAS 1806294-44-9)
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- 3-(2-(Aziridin-1-yl)ethoxy)-1-phenylisoquinoline (CAS 89721-21-1)
- Peptide-GMF (CAS CATO-CPTD788469)
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