2-Chloro-5-iodopyridine-3,4-diamine CAS 1363380-53-3
| CAS No. | 1363380-53-3 |
| Molecular Formula | C5H5ClIN3 |
| Molecular Weight | 269.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-5-iodopyridine-3,4-diamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Chloro-5-iodopyridine-3,4-diamine (CAS 1363380-53-3), molecular formula C5H5ClIN3 and molecular weight 269.47 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, chlorine/iodine substitution, 2-Chloro-5-iodopyridine-3,4-diamine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 269.47 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H5ClIN3 |
| Molecular Weight | 269.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-Chloro-5-iodo-N-methylpyrimidin-4-amine (CAS 1093847-70-1)
- 2-Chloro-3-iodo-4-methoxypyridine (CAS 1163693-01-3)
- 2-Chloro-4-iodo-5-methoxypyridine (CAS 1211516-07-2)
- 2-Chloro-5-iodo-4-methoxypyridine (CAS 1226878-98-3)
- 3-Chloro-2-iodo-5-methoxypyridine (CAS 1227499-70-8)
- 2-Chloro-3-iodo-5-methoxypyridine (CAS 1227578-09-7)
- 2-Chloro-3-iodo-6-methoxypyridine (CAS 1227580-90-6)
- 2-Chloro-4-iodo-3-methoxypyridine (CAS 1227592-88-2)
Recommended Standards
- (6-Chloro-5-iodopyridin-3-yl)methanol (CAS 1360938-13-1)
- 2-(Chloromethyl)-6-iodopyridin-4-ol (CAS 1393557-79-3)
- 2-Chloro-5-iodo-3-methoxypyridine (CAS 1352881-81-2)
- 4-(Chloromethyl)-6-iodopyridin-2-ol (CAS 1393583-70-4)
- N-hydroxy-2-thiazolecarboximidamide (CAS 89829-62-9)
- 2-(4-Fluorophenyl)-2-methylbutanoic acid (CAS 80854-29-1)
- 4,6-Dichloro-2,3-dimethylaniline (CAS 131885-26-2)
- 3-Chloro-2-(3-((2,4-dichlorophenoxy)methyl)-1H-1,2,4-triazol-1-yl)-5-(trifluoromethyl)pyridine (CAS 338395-63-4)
- Moxifloxacin Impurity 109 (CAS 1641561-55-8)
- 7-Methylimidazo[1,2-a]pyrazin-8(7H)-one (CAS 689297-90-3)
- Tert-butyl 4-((6-hydroxypyridazin-3-yl)oxy)piperidine-1-carboxylate (CAS 1219828-16-6)
- 7-bromo-[1,3]thiazolo[4,5-c]pyridin-2-amine (CAS 118801-75-5)
- 5-Bromo-3-methoxypyridin-2(1H)-one (CAS 1189757-62-7)
- endo-Gly31-Semaglutide (CAS CATO-C4X-2226282)
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