1-(Boc-amino)-3-fluorocyclobutanecarboxylic Acid CAS 1363381-27-4
| CAS No. | 1363381-27-4 |
| Molecular Formula | C10H16FNO4 |
| Molecular Weight | 233.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 233.24 g/mol gives 1-(Boc-amino)-3-fluorocyclobutanecarboxylic Acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(Boc-amino)-3-fluorocyclobutanecarboxylic Acid (CAS 1363381-27-4) is a high-purity analytical reference standard with the molecular formula C10H16FNO4 and a molecular weight of 233.24 g/mol.
The molecular framework of 1-(Boc-amino)-3-fluorocyclobutanecarboxylic Acid (C10H16FNO4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(Boc-amino)-3-fluorocyclobutanecarboxylic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H16FNO4 |
| Molecular Weight | 233.24 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 2,2'-((2,5-Diformyl-1,4-phenylene)bis(oxy))bis(N,N,N-trimethylethan-1-aminium)bromide (CAS 2830594-03-9)
- Tridocosanoin (CAS CATO-CCFD200472)
- 6,7-Dichlorochroman-4-one (CAS 27407-06-3)
- 4-Amino-3,3-dimethyl-piperidine-1-carboxylic acid tert-butyl ester hydrochloride (CAS 1965310-21-7)
- Ethyl 2-(4-(methoxycarbonyl)piperidin-1-yl)nicotinate (CAS 1185291-72-8)
- Ethyl 2-(5-methyl-3-(trifluoromethyl)-1h-pyrazol-1-yl)acetate (CAS 299405-24-6)
- (5-Methyl-3-phenylisoxazol-4-yl)(4-(2-nitro-4-(trifluoromethyl)phenyl)piperazin-1-yl)methanone (CAS 1012490-89-9)
- Ethyl pyridin-2-ylcarbamate (CAS 5255-67-4)
- 1-(2,6-Dimethylphenyl)-4-tosylpiperazine (CAS 713099-74-2)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
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