2-Thiaspiro[3.3]heptan-6-amine CAS 1363381-30-9
| CAS No. | 1363381-30-9 |
| Molecular Formula | C6H11NS |
| Molecular Weight | 129.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Thiaspiro[3.3]heptan-6-amine.
CATO supplies 2-Thiaspiro[3.3]heptan-6-amine (CAS 1363381-30-9), a certified reference material (molecular formula C6H11NS, MW 129.22 g/mol) for analytical method development and quality control.
The molecular framework of 2-Thiaspiro[3.3]heptan-6-amine (C6H11NS) is characterized by a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H11NS |
| Molecular Weight | 129.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Thiaspiro Standards
- 1-Oxa-6-thiaspiro[2.5]octane (CAS 185-73-9)
- 6-Oxa-1-thiaspiro[2.5]octane (CAS 86847-94-1)
- 2-thiaspiro[3.3]heptan-6-one (CAS 1523571-94-9)
- 4-Thiaspiro[2.5]octan-7-one (CAS 1369143-06-5)
- 6-Oxa-2-thiaspiro[3.3]heptane (CAS 174-80-1)
- 6-Thiaspiro[2.5]octan-1-amine (CAS 1249471-36-0)
- 2-Oxa-7-thiaspiro[3.5]nonane (CAS 2892449-71-5)
- 6-Methyl-2-thiaspiro[3.3]Heptan-6-ol (CAS 2411639-90-0)
Recommended Standards
- 6-Thia-2-azaspiro[3.4]Octane (CAS 1342178-21-5)
- 2-cyclobutylethanethioamide (CAS 1468689-96-4)
- 3,3-Dimethylpyrrolidine-2-thione (CAS 127103-83-7)
- 2-Thia-6-azaspiro[3.4]octane (CAS 1498161-47-9)
- Tert-butyl (2R,4R)-2-cyano-4-hydroxypyrrolidine-1-carboxylate (CAS 1932029-59-8)
- 3,6-Bis(4-bromophenyl)-2,5-bis(2-ethylhexyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione (CAS 852434-82-3)
- n-[4-(4-tert-butylphenyl)-1,3-thiazol-2-yl]-4-(morpholine-4-sulfonyl)benzamide (CAS 380453-39-4)
- trans-4-(4-Cyanobenzoyl)cyclohexane-1-carboxylic acid (CAS 736136-09-7)
- Amino-(2-nitro-phenyl)-acetic acid (CAS 50381-53-8)
- Estradiol Valerate 17α-Isomer (CAS 182624-54-0)
- 4-Chloro-6-phenyl-1,3,5-triazin-2-amine (CAS 3842-53-3)
- 3-Amino-4-chloro-N,N-diethylbenzamide (CAS 905811-02-1)
- 1,3-Propanediol, 2,2-bis(hydroxymethyl)-, homopolymer, heptanoate isononanoate (CAS 70693-37-7)
- Insulin Detemir (CAS 169148-63-4)
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