cis-tert-Butyl 3-hydroxy-2,2,4,4-(tetramethyl)cyclobutylcarbamate CAS 1363381-85-4
| CAS No. | 1363381-85-4 |
| Molecular Formula | C13H25NO3 |
| Molecular Weight | 243.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
cis-tert-Butyl 3-hydroxy-2,2,4,4-(tetramethyl)cyclobutylcarbamate (C13H25NO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies cis-tert-Butyl 3-hydroxy-2,2,4,4-(tetramethyl)cyclobutylcarbamate (CAS 1363381-85-4), a certified reference material (molecular formula C13H25NO3, MW 243.34 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), cis-tert-Butyl 3-hydroxy-2,2,4,4-(tetramethyl)cyclobutylcarbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H25NO3 |
| Molecular Weight | 243.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Recommended Standards
- Tert-butyl (1-(hydroxymethyl)-4-methylcyclohexyl)carbamate (CAS 1343661-98-2)
- Tert-butyl 4-(1-hydroxyethyl)azepane-1-carboxylate (CAS 1401303-71-6)
- trans-tert-Butyl ((1r,3r)-3-hydroxy-2,2,4,4-tetramethylcyclobutyl)carbamate (CAS 1338812-41-1)
- Tert-butyl (4-(2-hydroxyethyl)cyclohexyl)carbamate (CAS 1403764-89-5)
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