trans-tert-butyl 3-hydroxy-3-methylcyclobutylcarbamate CAS 1363382-14-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including trans-tert-butyl 3-hydroxy-3-methylcyclobutylcarbamate.

CATO supplies trans-tert-butyl 3-hydroxy-3-methylcyclobutylcarbamate (CAS 1363382-14-2), a certified reference material (molecular formula C10H19NO3, MW 201.26 g/mol) for analytical method development and quality control.

Structurally, trans-tert-butyl 3-hydroxy-3-methylcyclobutylcarbamate (C10H19NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 201.26 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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