tert-Butyl (2S)-2-(aminomethyl)-4,4-difluoropyrrolidine-1-carboxylate CAS 1363384-67-1
| CAS No. | 1363384-67-1 |
| Molecular Formula | C10H18F2N2O2 |
| Molecular Weight | 236.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
tert-Butyl (2S)-2-(aminomethyl)-4,4-difluoropyrrolidine-1-carboxylate (CAS 1363384-67-1) is a high-purity analytical reference standard with the molecular formula C10H18F2N2O2 and a molecular weight of 236.26 g/mol.
The molecular framework of tert-Butyl (2S)-2-(aminomethyl)-4,4-difluoropyrrolidine-1-carboxylate (C10H18F2N2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), tert-Butyl (2S)-2-(aminomethyl)-4,4-difluoropyrrolidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H18F2N2O2 |
| Molecular Weight | 236.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- (S)-tert-Butyl ((4,4-difluoropyrrolidin-2-yl)methyl)carbamate (CAS 1363384-66-0)
- 1-Cyclohexyl-6,7-difluoro-1,3-benzodiazole (CAS 1365272-58-7)
- tert-Butyl N-[1-(aminomethyl)-3,3-difluorocyclobutyl]carbamate (CAS 1363382-43-7)
- Ethyl 2-(4-ethoxy-2-methylphenyl)-2-oxoacetate (CAS 1368196-72-8)
- 1-(1H-benzo[d][1,2,3]triazol-1-yl)butan-2-one (CAS 302966-90-1)
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- 2-tert-Butyl-4-thiazolecarboxylic Acid Ethyl Ester (CAS 1197010-34-6)
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- 5-Bromo-N-(cyclopentylmethyl)-3-methylpyridin-2-amine (CAS 1541496-20-1)
- C-Peptide 2 (rat) (CAS 41594-08-5)
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