4-Amino-1-((2R,5S)-2-((tert-butyldimethylsilyloxy)methyl)-1,3-oxathiolan-5-yl)-5-fluoropyrimidin-2(1H)-one CAS 1365246-84-9
| CAS No. | 1365246-84-9 |
| Molecular Formula | C14H24FN3O3SSi |
| Molecular Weight | 361.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 361.51 g/mol gives 4-Amino-1-((2R,5S)-2-((tert-butyldimethylsilyloxy)methyl)-1,3-oxathiolan-5-yl)-5-fluoropyrimidin-2(1H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Amino-1-((2R,5S)-2-((tert-butyldimethylsilyloxy)methyl)-1,3-oxathiolan-5-yl)-5-fluoropyrimidin-2(1H)-one (CAS 1365246-84-9) is a high-purity analytical reference standard with the molecular formula C14H24FN3O3SSi and a molecular weight of 361.51 g/mol.
4-Amino-1-((2R,5S)-2-((tert-butyldimethylsilyloxy)methyl)-1,3-oxathiolan-5-yl)-5-fluoropyrimidin-2(1H)-one (C14H24FN3O3SSi) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Amino-1-((2R,5S)-2-((tert-butyldimethylsilyloxy)methyl)-1,3-oxathiolan-5-yl)-5-fluoropyrimidin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H24FN3O3SSi |
| Molecular Weight | 361.51 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- [1-((S)-2-Amino-propionyl)-piperidin-4-ylmethyl]-isopropyl-carbamic acid benzyl ester (CAS 1353993-47-1)
- [1-((S)-2-Amino-3-methyl-butyryl)-piperidin-4-yl]-methyl-carbamic acid benzyl ester (CAS 1354007-82-1)
- 3-{[((S)-2-Amino-3-methyl-butyryl)-ethyl-amino]-methyl}-pyrrolidine-1-carboxylic acid benzyl ester (CAS 1354014-98-4)
- 2-((4-Amino-5-cyclohexyl-4H-1,2,4-triazol-3-yl)thio)-N-(2-methoxyphenyl)acetamide (CAS 840514-95-6)
- 3-Amino-N-(4-methoxyphenyl)-4-(piperidin-1-yl)benzene-1-sulfonamide (CAS 326092-19-7)
- 5-Amino-N-(2-methoxyphenyl)-2-(piperidin-1-yl)benzene-1-sulfonamide (CAS 326022-99-5)
- 5-Amino-N-(4-methoxyphenyl)-2-(piperidin-1-yl)benzene-1-sulfonamide (CAS 326034-12-2)
- N-(4-(4-Amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl)methanesulfonamide (CAS 532959-63-0)
Recommended Standards
- N-Cycloheptyl-2-((5-propyl-4-(1H-pyrrol-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 896296-01-8)
- 5-Ethyl 1-isobutyl 6-(trimethylsilyl)-1H-indole-1,5-dicarboxylate (CAS 153602-84-7)
- N1,N1-Diethyl-N6-(5-fluoro-6-methoxy-4-methylquinolin-8-yl)hexane-1,6-diamine (CAS 64993-13-1)
- 2-(Chloromethyl)-6-(difluoromethyl)-4-iodopyridine-3-acetic acid (CAS 1805197-33-4)
- 4-Bromo-N-(2-chlorophenyl)benzamide (CAS 313268-56-3)
- 4-(3-Hydroxypropyl)morpholine (CAS 4441-30-9)
- 8-Methyl-5,8-diazaspiro[3.5]nonane-6,9-dione (CAS 2098036-60-1)
- Ethyl 1-(4-fluorophenyl)-1h,4h,5h,6h-cyclopenta[c]pyrazole-3-carboxylate (CAS 123345-71-1)
- 2-(8-Oxa-3-azabicyclo[3.2.1]Octan-3-yl)ethan-1-amine (CAS 54746-29-1)
- 2-(4-Chlorophenyl)-N-[(1E)-{[(4-chlorophenyl)methoxy]imino}methyl]-2-[3-(trifluoromethyl)quinoxalin-2-yl]acetamide (CAS 477867-65-5)
- N-((1-(sec-Butyl)-1H-pyrazol-5-yl)methyl)-1-ethyl-1H-pyrazol-4-amine hydrochloride (CAS 1856066-20-0)
- 3-Phenylisoquinolin-4-ol (CAS 51787-73-6)
- 2-(2,3-Dichlorophenoxy)propanoic acid (CAS 55507-94-3)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com