4-(1-Chloro-2-(methylamino)ethyl)phenyl acetate CAS 136529-69-6
| CAS No. | 136529-69-6 |
| Molecular Formula | C11H14ClNO2 |
| Molecular Weight | 227.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(1-Chloro-2-(methylamino)ethyl)phenyl acetate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(1-Chloro-2-(methylamino)ethyl)phenyl acetate (CAS 136529-69-6), molecular formula C11H14ClNO2 and molecular weight 227.69 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(1-Chloro-2-(methylamino)ethyl)phenyl acetate (C11H14ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(1-Chloro-2-(methylamino)ethyl)phenyl acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H14ClNO2 |
| Molecular Weight | 227.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 3-(2-Chloro-5-methylphenyl)benzonitrile (CAS 1365272-10-1)
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- 2-(2-Chloro-3,4-dimethoxyphenyl)azetidine (CAS 1391304-77-0)
- m-Tolunitrile (CAS 620-22-4)
- Oct-5-ynamide (CAS 855376-60-2)
- 1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)heptane-3,5-dione (CAS 149579-07-7)
- 1-[4-(Pyridin-3-ylmethoxy)-phenyl]-piperazine trihydrochloride (CAS 1187928-13-7)
- 3,8-Dimethyl-3-(4-methylpent-3-en-1-yl)-3,11-dihydropyrano[3,2-a]carbazol-9-ol (CAS 144606-95-1)
- Lercanidipine Impurity 7 (CAS 100442-33-9)
- 2-(3-Methyl-1,2,4-oxadiazol-5-yl)-1H-indole (CAS 1239735-68-2)
- Mirabegron Impurity 46 (CAS CATO-C4X-103246)
- N-[4-(aminomethyl)phenyl]-2-hydroxybenzamide (CAS 926271-67-2)
- (Gly1,Ser3·22,Gln?·3?,Thr?,Arg1?,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) (CAS 313988-89-5)
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