2-(Piperazin-1-yl)-N-(2-(trifluoromethyl)phenyl)acetamide dihydrochloride CAS 1365836-40-3
| CAS No. | 1365836-40-3 |
| Molecular Formula | C13H16F3N3O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(Piperazin-1-yl)-N-(2-(trifluoromethyl)phenyl)acetamide dihydrochloride (C13H16F3N3OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(Piperazin-1-yl)-N-(2-(trifluoromethyl)phenyl)acetamide dihydrochloride (CAS 1365836-40-3) is a high-purity analytical reference standard with the molecular formula C13H16F3N3OHCl and a molecular weight of 323.74 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(Piperazin-1-yl)-N-(2-(trifluoromethyl)phenyl)acetamide dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H16F3N3O 2*HCl |
| Molecular Weight | 323.74 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Piperazin Standards
- 2-(3-(Piperazin-1-yl)propyl)isoindoline-1,3-dione (CAS 1000547-80-7)
- (4-Methyl-piperazin-1-yl)-(S)-pyrrolidin-2-yl-methanone (CAS 100158-68-7)
- (6-(Piperazin-1-yl)pyridin-3-yl)boronic acid (CAS 1003043-67-1)
- (2-(Piperazin-1-yl)pyridin-4-yl)boronic acid (CAS 1003043-70-6)
- N-(4-(Piperazin-1-ylsulfonyl)phenyl)acetamide (CAS 100318-71-6)
- Piperazin-1-yl(m-tolyl)methanone hydrochloride (CAS 100940-01-0)
- 2-(Piperazin-1-yl)phenol (CAS 1011-17-2)
- 2-phenyl-1-(piperazin-1-yl)butan-1-one (CAS 1016503-45-9)
Recommended Standards
- rel-Methyl (1R,2R)-2-aminocyclobutane-1-carboxylate (CAS 1807558-23-1)
- Ethyl 5-(4-methoxyphenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 667920-67-4)
- Isatoribine (CAS 122970-40-5)
- (R)-1-(3-Ethynylphenyl)ethan-1-ol (CAS 2227716-99-4)
- N-((S)-1-(4-((R)-Pyrrolidin-3-yloxy)phenyl)ethyl)acetamide (CAS 1594129-72-2)
- Methyl 1-phenyl-5-thioxopyrrolidine-3-carboxylate (CAS 1086375-83-8)
- tert-Butyl N-[2-amino-2-(3,4-dimethoxyphenyl)ethyl]carbamate (CAS 912762-97-1)
- 2-(2-Hydroxy-2-methylpropoxy)isoindoline-1,3-dione (CAS 1009334-87-5)
- Bempedoic Acid Impurity 25 (CAS 2511500-14-2)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
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