5-Bromo-7-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole CAS 1365889-34-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1365889-34-4
Molecular FormulaC12H12BrFN2O
Molecular Weight299.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromo-7-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole CAS 1365889-34-4 chemical structure

Description

The occurrence of 5-Bromo-7-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Bromo-7-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole (CAS 1365889-34-4) is a high-purity analytical reference standard with the molecular formula C12H12BrFN2O and a molecular weight of 299.14 g/mol.

5-Bromo-7-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole (C12H12BrFN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Bromo-7-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H12BrFN2O
Molecular Weight299.14 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF/Br-containing
Nitrogen Atoms2

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