4-Ethoxy-1,1,1-trifluoro-4-piperidin-1-yl-but-3-en-2-one CAS 1365994-83-7
| CAS No. | 1365994-83-7 |
| Molecular Formula | C11H16F3NO2 |
| Molecular Weight | 251.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Ethoxy-1,1,1-trifluoro-4-piperidin-1-yl-but-3-en-2-one (C11H16F3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
4-Ethoxy-1,1,1-trifluoro-4-piperidin-1-yl-but-3-en-2-one (CAS 1365994-83-7), molecular formula C11H16F3NO2 and molecular weight 251.25 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Ethoxy-1,1,1-trifluoro-4-piperidin-1-yl-but-3-en-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H16F3NO2 |
| Molecular Weight | 251.25 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethoxy Standards
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Recommended Standards
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- 1-(4-Fluorobenzoyl)piperidine-4-carboxylic acid (CAS 139679-45-1)
- Methyl 1-(4-fluorobenzyl)-5-oxopyrrolidine-3-carboxylate (CAS 1171317-52-4)
- 4-Amino-4'-fluoro[1,1'-biphenyl]-3-carboxylic acid (CAS 885268-20-2)
- 5-Iodo-1-methyl-1h-1,2,3-triazole (CAS 1196152-43-8)
- Bis(1,3-dithian-2-yl)methane-d (CAS 31401-53-3)
- (S)-1-(4-chloro-3-fluorophenyl)-2,2,2-trifluoroethan-1-amine (CAS 1213569-46-0)
- 3-(4-Methylpiperazin-1-yl)benzoic Acid (CAS 215309-01-6)
- 1-(pyridin-2-ylmethyl)-1H-pyrrole-2-carboxylic acid (CAS 896049-13-1)
- 309727-48-8 5-[2-Chloro-5-(trifluoromethyl)phenoxy]-2-nitrophenol 9811AD C13H7ClF3NO4 (CAS 309727-48-8)
- Ethyl 5-bromo-4-fluoro-2-methoxybenzoate (CAS 2114116-71-9)
- 5-(Trifluoromethyl)quinolin-4(1H)-one (CAS 1261845-42-4)
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