1-{5-bromopyrrolo[2,1-f][1,2,4]triazin-7-yl}ethan-1-one CAS 1367933-48-9
| CAS No. | 1367933-48-9 |
| Molecular Formula | C8H14BrN3O |
| Molecular Weight | 248.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-{5-bromopyrrolo[2,1-f][1,2,4]triazin-7-yl}ethan-1-one.
1-{5-bromopyrrolo[2,1-f][1,2,4]triazin-7-yl}ethan-1-one (CAS 1367933-48-9) is a high-purity analytical reference standard with the molecular formula C8H14BrN3O and a molecular weight of 248.12 g/mol.
The molecular framework of 1-{5-bromopyrrolo[2,1-f][1,2,4]triazin-7-yl}ethan-1-one (C8H14BrN3O) is characterized by an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H14BrN3O |
| Molecular Weight | 248.12 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related bromopyrrolo Standards
- 1-{7-bromopyrrolo[2,1-f][1,2,4]triazin-2-yl}ethan-1-one (CAS 1369138-52-2)
- 1-{5-bromopyrrolo[2,1-f][1,2,4]triazin-2-yl}ethan-1-one (CAS 1369342-68-6)
- 6-Bromopyrrolo[2,3,4-de]isoquinolin-2(1H)-one (CAS 2504236-88-6)
- 6-Bromopyrrolo[4,3,2-ij]isoquinolin-2(1H)-one (CAS 2504236-83-1)
- 8-Bromopyrrolo[2,3,4-de]quinolin-5(4H)-one (CAS 2767589-36-4)
- 1-{7-bromopyrrolo[2,1-f][1,2,4]triazin-2-yl}ethan-1-amine (CAS 1367942-44-6)
- 1-{5-bromopyrrolo[2,1-f][1,2,4]triazin-2-yl}ethan-1-amine (CAS 1369114-43-1)
- 2-{5-bromopyrrolo[2,1-f][1,2,4]triazin-7-yl}ethan-1-amine (CAS 1781830-19-0)
Recommended Standards
- 5-Bromo-[1,1'-biphenyl]-3-amine (CAS 136649-27-9)
- 3-Bromo-1-(tetrahydro-2H-pyran-4-yl)pyrrolidin-2-one (CAS 1344276-66-9)
- 3-bromothiophene-2-carbonyl isothiocyanate (CAS 1339908-68-7)
- 4-Bromo-N-methoxy-N-methylcyclohex-3-ene-1-carboxamide (CAS 1375069-25-2)
- 2-Hydroxyethanesulphonic acid (CAS 107-36-8)
- 1,2-Dipalmitoyl-3-O-benzyl-sn-glycerol (CAS 30403-51-1)
- N-Phenyl-2-((3-(pyridin-3-yl)-1H-1,2,4-triazol-5-yl)thio)acetamide (CAS 332157-94-5)
- 3-((2-Bromo-6-ethoxy-4-formylphenoxy)methyl)benzoic acid (CAS 426221-11-6)
- 2-(methylamino)-1-{4-[(3-methylphenyl)methyl]piperazin-1-yl}ethan-1-one (CAS 900641-45-4)
- 3-(3-Fluoro-4-methylphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 956202-54-3)
- 1-Iodo-4-nitro-2-(trifluoromethyl)benzene (CAS 400-75-9)
- Di-4-chlorophenyl iodonium bromide (CAS 26018-88-2)
- 6-Benzyl-6-azaspiro[2.5]octan-4-one (CAS 1101987-18-1)
- [D-Phe22]Semaglutide (CAS CATO-C4X-2226222)
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