Ethyl 2-amino-6-bromo-7-methoxybenzo[b]thiophene-3-carboxylate CAS 136800-72-1
| CAS No. | 136800-72-1 |
| Molecular Formula | C12H12BrNO3S |
| Molecular Weight | 330.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-amino-6-bromo-7-methoxybenzo[b]thiophene-3-carboxylate.
Ethyl 2-amino-6-bromo-7-methoxybenzo[b]thiophene-3-carboxylate (CAS 136800-72-1), molecular formula C12H12BrNO3S and molecular weight 330.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 2-amino-6-bromo-7-methoxybenzo[b]thiophene-3-carboxylate (C12H12BrNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12BrNO3S |
| Molecular Weight | 330.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
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Recommended Standards
- n-(4-Bromophenyl)-3,5-dimethyl-1h-pyrazole-4-sulfonamide (CAS 1268702-85-7)
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- 5-((2-(3-Bromophenoxy)ethyl)thio)-4-methyl-2,4-dihydro-3h-1,2,4-triazol-3-one (CAS 1223303-37-4)
- (5-hydroxy-6-methyl-4-(((2,2,2-trifluoroethyl)amino)methyl)pyridin-3-yl)methyl dihydrogen phosphate (CAS 59087-16-0)
- trans-2-Butenylpyrophosphate (CAS 22342-68-3)
- (E)-4-Oxodec-2-enal (CAS 92464-81-8)
- 1-(3,5-Dimethoxyphenyl)propan-1-one (CAS 41497-31-8)
- Methyl 2-[(4-Amino-6-chloro-3-pyridyl)oxy]acetate (CAS 1823872-37-2)
- 2-(4-Benzyl-1-piperidinyl)aniline (CAS 455260-03-4)
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- 7-Bromo-6-chloro-3,4-dihydronaphthalen-1(2H)-one (CAS 159639-64-2)
- deleobuvir (CAS 863884-77-9)
- Biotinyl-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802086-28-7)
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