8-Fluoroisoquinoline-5-carboxylic acid CAS 1368079-46-2
| CAS No. | 1368079-46-2 |
| Molecular Formula | C10H6FNO2 |
| Molecular Weight | 191.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
8-Fluoroisoquinoline-5-carboxylic acid (CAS 1368079-46-2), molecular formula C10H6FNO2 and molecular weight 191.16 g/mol, is a CATO reference standard with documented purity and traceability.
8-Fluoroisoquinoline-5-carboxylic acid (C10H6FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 8-Fluoroisoquinoline-5-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6FNO2 |
| Molecular Weight | 191.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoroisoquinoline Standards
- 3-Fluoroisoquinoline-6-carboxylic acid (CAS 1104071-70-6)
- 3-Fluoroisoquinoline-1-carboxylic acid (CAS 1179148-90-3)
- 5-Fluoroisoquinoline-1-carboxylic acid (CAS 1179149-35-9)
- 6-Fluoroisoquinoline-1-carboxylic acid (CAS 1179149-37-1)
- 6-Fluoroisoquinoline-5-carboxylic acid (CAS 1260835-91-3)
- 7-Fluoroisoquinoline-5-carboxylic acid (CAS 1368043-44-0)
- 5-Fluoroisoquinoline-8-carboxylic acid (CAS 1369177-56-9)
- 8-Fluoroisoquinoline-1-carboxylic acid (CAS 1780197-11-6)
Recommended Standards
- 6-Fluoroquinoline-8-carboxylic acid (CAS 1306605-84-4)
- 1-Fluoro-5-nitronaphthalene (CAS 13720-44-0)
- (E)-3-(3-CYANO-2-FLUOROPHENYL)ACRYLIC ACID (CAS 1262014-59-4)
- 5-(3-Fluorophenyl)oxazole-4-carbaldehyde (CAS 1384066-97-0)
- N-Cyclohexyl-N-ethyl-2-pyrrolidinecarboxamidehydrochloride (CAS 1236262-24-0)
- Exatecan mesylate (CAS 169869-90-3)
- N-(5-Amino-2-methylphenyl)-2,4-dichlorobenzamide (CAS 303062-60-4)
- 3-((Tert-butoxycarbonyl)(methyl)amino)thietane-3-carboxylic acid (CAS 1935644-97-5)
- 1-(Cyclopropylmethyl)-L-proline (CAS 342793-01-5)
- 4H,5H,6H-pyrrolo[1,2-b]pyrazol-3-amine (CAS 1479085-37-4)
- (2R,7AR)-hexahydro-1H-pyrrolizine-2-carbonitrile (CAS 172339-59-2)
- 2-Amino-2-(3,4,5-trimethoxyphenyl)acetic acid (CAS 86053-97-6)
- 3-(4,5-Dimethylbenzo[h][1,6]naphthyridin-2-yl)-2-methylquinolin-4-amine (CAS 71993-16-3)
- Semaglutide impurity 197 (CAS CATO-C4X-2226197)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com