(7-Chloroimidazo[1,2-a]pyridin-2-yl)methanol CAS 1368290-38-3
| CAS No. | 1368290-38-3 |
| Molecular Formula | C8H7ClN2O |
| Molecular Weight | 182.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(7-Chloroimidazo[1,2-a]pyridin-2-yl)methanol (CAS 1368290-38-3) is a high-purity analytical reference standard with the molecular formula C8H7ClN2O and a molecular weight of 182.61 g/mol.
Structurally, (7-Chloroimidazo[1,2-a]pyridin-2-yl)methanol (C8H7ClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 182.61 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7ClN2O |
| Molecular Weight | 182.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloroimidazo Standards
- (7-Chloroimidazo[1,2-a]pyridin-3-yl)methanol (CAS 1367992-89-9)
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- (3-Chloroimidazo[1,2-a]pyridin-5-yl)methanol (CAS 167884-19-7)
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- (5-Chloroimidazo[1,2-a]pyridin-2-yl)methanol (CAS 342024-46-8)
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- Semaglutide impurity 74 (CAS CATO-C4X-222674)
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