4-(4-Hydroxymethyl-3-methoxyphenoxy)-butyric acid CAS 136849-75-7
| CAS No. | 136849-75-7 |
| Molecular Formula | C12H16O5 |
| Molecular Weight | 240.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-(4-Hydroxymethyl-3-methoxyphenoxy)-butyric acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 4-(4-Hydroxymethyl-3-methoxyphenoxy)-butyric acid (CAS 136849-75-7), a certified reference material (molecular formula C12H16O5, MW 240.25 g/mol) for analytical method development and quality control.
The molecular framework of 4-(4-Hydroxymethyl-3-methoxyphenoxy)-butyric acid (C12H16O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H16O5 |
| Molecular Weight | 240.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
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Recommended Standards
- 3,5-Difluoro-4-((2-hydroxypentyl)amino)benzonitrile (CAS 1355531-74-6)
- 2-Acetoxybenzophenone (CAS 138711-39-4)
- n-(6-Fluorobenzo[d]thiazol-2-yl)-N-methylglycine (CAS 1352999-06-4)
- 3-Benzoyloxyacetophenone (CAS 139-28-6)
- Ethyl 4-formyl-1-(4-nitrophenyl)-1H-pyrazole-3-carboxylate (CAS 849618-72-0)
- (E)-({4-[4-(3-chlorobenzoyl)-1,4-diazepan-1-yl]-3-nitrophenyl}methylidene)(methoxy)amine (CAS 691869-11-1)
- Ethyl (S)-2-hydroxy-2-(4-iodophenyl)acetate (CAS 1579992-43-0)
- 4-Fluoro-N,N-dimethylaniline (CAS 403-46-3)
- 1,3-bis(4-cyanophenyl)urea (CAS 100953-84-2)
- 6-Bromo-5-(difluoromethyl)-4-methylpyridin-2-ol (CAS 1805245-56-0)
- 1-(propan-2-yl)-7-oxa-2-azaspiro[3.5]nonane hydrochloride (CAS 1955553-91-9)
- 1-(3-Methoxypropanoyl)piperidine-4-carboxylic acid (CAS 1099048-74-4)
- 2-(3,5-Dimethylpiperidine-1-carbonyl)aniline (CAS 926272-60-8)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
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