2-(4-Acetylpiperazin-1-yl)pyrimidine-5-carboxylic acid CAS 1368568-08-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1368568-08-4
Molecular FormulaC11H14N4O3
Molecular Weight250.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(4-Acetylpiperazin-1-yl)pyrimidine-5-carboxylic acid CAS 1368568-08-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 250.25 g/mol gives 2-(4-Acetylpiperazin-1-yl)pyrimidine-5-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-(4-Acetylpiperazin-1-yl)pyrimidine-5-carboxylic acid (CAS 1368568-08-4), a certified reference material (molecular formula C11H14N4O3, MW 250.25 g/mol) for analytical method development and quality control.

The molecular framework of 2-(4-Acetylpiperazin-1-yl)pyrimidine-5-carboxylic acid (C11H14N4O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H14N4O3
Molecular Weight250.25 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Nitrogen Atoms4

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