5-chloro-4-methoxy-2-methylbenzene-1-sulfonamide CAS 1368892-59-4
| CAS No. | 1368892-59-4 |
| Molecular Formula | C8H10ClNO3S |
| Molecular Weight | 235.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-chloro-4-methoxy-2-methylbenzene-1-sulfonamide (CAS 1368892-59-4) is a high-purity analytical reference standard with the molecular formula C8H10ClNO3S and a molecular weight of 235.69 g/mol.
The molecular framework of 5-chloro-4-methoxy-2-methylbenzene-1-sulfonamide (C8H10ClNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-chloro-4-methoxy-2-methylbenzene-1-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10ClNO3S |
| Molecular Weight | 235.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related chloro Standards
- methyl 4-chloro-2-(propan-2-yloxy)-1,3-thiazole-5-carboxylate (CAS 1183881-54-0)
- 4-Chloro-2-(thiophen-2-yl)pyrazolo[1,5-a]pyrazine (CAS 1255784-69-0)
- 6-Chloro-N-ethyl-2-(methylsulfonyl)pyrimidin-4-amine (CAS 1289386-46-4)
- 5-Chloro-4-(dimethylamino)pyridine-3-sulfonamide (CAS 1352514-86-3)
- 6-Chloro-N,N-dimethyl-2-(methylsulfonyl)pyrimidin-4-amine (CAS 1353959-30-4)
- n-(3-Chloro-4-methoxyphenyl)methanesulfonamide (CAS 1491837-52-5)
- 3-chloro-5-(methoxymethyl)benzene-1-sulfonamide (CAS 1549835-54-2)
- 2-chloro-4H,5H-thieno[3,2-c]isoquinolin-5-one (CAS 2259671-16-2)
Recommended Standards
- 5-Chlorothiabendazole (CAS 142383-75-3)
- 4-Amino-5-chloro-N,N-dimethylpyridine-3-sulfonamide (CAS 1352521-16-4)
- 5-(propan-2-yloxy)pyridine-3-sulfonyl chloride (CAS 1545127-49-8)
- 3-(3-Amino-4-chloro-1h-pyrazol-1-yl)tetrahydrothiophene 1,1-dioxide (CAS 1342779-17-2)
- 4-Phenoxyphthalic acid (CAS 37951-15-8)
- (5-methylpyridazin-3-yl)methanamine hydrochloride (CAS 1788054-82-9)
- 3-(2-Hydroxyphenyl)-N-(1h-pyrazol-3-yl)propanamide (CAS 1241067-13-9)
- 4-(N-Methylsulfamoyl)phenylboronic Acid (CAS 226396-31-2)
- 2-(7-Fluoro-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)acetic acid (CAS 1514726-22-7)
- 3,3-Diphenylpropanal (CAS 4279-81-6)
- Rel-(2R,3R)-3-((tert-Butoxycarbonyl)amino)-2-hydroxy-3-(4-Methoxyphenyl)propanoic acid (CAS 1217648-00-4)
- 1-Benzyl-3-bromopyridin-2(1h)-one (CAS 1304770-95-3)
- 3-Ethyl-5-(furan-2-yl)-2-sulfanyl-3h,4h-thieno[2,3-d]pyrimidin-4-one (CAS 852933-44-9)
- Brain Injury Derived Neurotrophic Peptide (H-3914.0001) (CAS 148330-12-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com