1,4-Diethynyl-2-fluorobenzene CAS 137000-66-9
| CAS No. | 137000-66-9 |
| Molecular Formula | C10H5F |
| Molecular Weight | 144.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,4-Diethynyl-2-fluorobenzene.
1,4-Diethynyl-2-fluorobenzene (CAS 137000-66-9), molecular formula C10H5F and molecular weight 144.15 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to fluorine substitution, an aromatic ring system, 1,4-Diethynyl-2-fluorobenzene is typically pale yellow to yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 144.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1,4-Diethynyl-2-fluorobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5F |
| Molecular Weight | 144.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
Related Diethynyl Standards
- 1,2-Diethynyl-3-fluorobenzene (CAS 412041-38-4)
- 1,2-Diethynyl-4-fluorobenzene (CAS 336106-79-7)
- 1,3-Diethynyl-5-fluorobenzene (CAS 219633-74-6)
- 1,5-Diethynyl-2,4-dimethylbenzene (CAS 1379822-09-9)
- 1,2-diethynyl-4,5-dimethylbenzene (CAS 46037-61-0)
- 1,4-Diethynyl-2,5-dimethylbenzene (CAS 75867-45-7)
- 1,5-Diethynyl-2,4-difluorobenzene (CAS 1379822-11-3)
- 1,4-Diethynyl-2,3-difluorobenzene (CAS 1430403-93-2)
Recommended Standards
- 4-Amino-5-thiazolecarboxylic acid (CAS 1353101-89-9)
- 5-Aminoisothiazole-3-carboxylic acid (CAS 1416374-24-7)
- 5-Aminothiazole-4-carboxylic acid (CAS 1353101-13-9)
- [1-(2-Fluoro-ethyl)-1h-pyrazol-3-yl]-methanol (CAS 1427021-99-5)
- Methyl 2-bromo-3-(benzyloxy)-6-fluorobenzoate (CAS 2484888-81-3)
- 6-Bromo-4,5-difluoro-3H-1,2,3-benzotriazole (CAS 1381944-47-3)
- 4-(Hydrazinylmethyl)-N,N-dimethylaniline hydrochloride (CAS 93335-92-3)
- N-Methyl-1-(piperidin-2-yl)-N-((1,3,5-trimethyl-1H-pyrazol-4-yl)methyl)methanamine (CAS 1707400-41-6)
- N-[2-(4-Ethylphenoxy)propyl]-4-fluoroaniline (CAS 1040687-51-1)
- ent-Fasiglifam (TAK-875) (CAS 1234474-57-7)
- 2-Decenal (CAS 3913-71-1)
- Glipizide Impurity 43 (CAS CATO-C4X-140743)
- 3-Benzyl-7-(2-methoxyethyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione (CAS 554423-81-3)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
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