trans-4′-(4-Ethylcyclohexyl)-3,4,5-trifluoro-1,1′-biphenyl CAS 137019-94-4
| CAS No. | 137019-94-4 |
| Molecular Formula | C20H21F3 |
| Molecular Weight | 318.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
trans-4′-(4-Ethylcyclohexyl)-3,4,5-trifluoro-1,1′-biphenyl (CAS 137019-94-4), molecular formula C20H21F3 and molecular weight 318.38 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of trans-4′-(4-Ethylcyclohexyl)-3,4,5-trifluoro-1,1′-biphenyl (C20H21F3) is characterized by fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C20H21F3 |
| Molecular Weight | 318.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
Related trans Standards
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