Posaconazole Impurity 40 CAS 1370190-94-5
| CAS No. | 1370190-94-5 |
| Molecular Formula | C35H40F2N8O4 |
| Molecular Weight | 674.74 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 674.74 g/mol gives Posaconazole Impurity 40 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Posaconazole Impurity 40 (CAS 1370190-94-5) is a certified pharmaceutical impurity reference standard with the molecular formula C35H40F2N8O4 and a molecular weight of 674.74 g/mol.
Structurally, Posaconazole Impurity 40 (C35H40F2N8O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 19.0, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 674.74 g/mol, it falls into the high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Posaconazole Impurity 40 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C35H40F2N8O4 |
| Molecular Weight | 674.74 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Posaconazole Standards
- Posaconazole Impurity 38 (CAS CATO-C4X-120838)
- Posaconazole Impurity 173 (CAS CATO-C4X-1208173)
- Posaconazole Impurity 100 (CAS CATO-C4X-1208100)
- Posaconazole Impurity 172 (CAS CATO-C4X-1208172)
- Posaconazole Impurity 60 (CAS CATO-C4X-120860)
- Posaconazole Impurity 65 (CAS CATO-C4X-120865)
- Posaconazole Impurity 161 (CAS CATO-C4X-1208161)
- Posaconazole Impurity 45 (CAS 1388148-30-8)
Recommended Standards
- DBCO-PEG4-Maleimide (CAS 1480516-75-3)
- Olmesartan Impurity 44 (CAS CATO-C4X-109744)
- Ceftazidime Impurity 86 (CAS CATO-C4X-121286)
- 2,3,4,6-Tetra-o-benzyl-alpha-d-glucopyranosyl n,n,n',n'-tetramethylphosphorodiamidate (ca. 20% In benzene) (CAS 143520-19-8)
- rac-Clemastine Fumarate EP Impurity B HCl (CAS 61771-18-4 (free base))
- Axitinib Impurity 170 (CAS CATO-C4X-107170)
- Landiolol Impurity 120 (CAS CATO-C4X-2621120)
- N-((3-chloropyrazin-2-yl)methyl)cyclopropanamine hydrochloride (CAS 1353979-80-2)
- 2,4-Dimethoxybenzenesulfonyl chloride (CAS 63624-28-2)
- Fluorescein-6-carbonyl-Tyr-Val-Ala-DL-Asp(OMe)-fluoromethylketone (CAS 1926163-69-0)
- Naphthalen-2-yl(pyridin-2-yl)methanol (CAS 1273957-37-1)
- n,7-Dimethylimidazo[1,2-a]pyridine-2-carboxamide (CAS 1223636-27-8)
- (3-Chloropropoxy)cyclohexane (CAS 221194-62-3)
- Antistasin-Related Peptide (CAS 161561-46-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com