2-chloro-N-(3,3-diphenylpropyl)acetamide CAS 137075-21-9
| CAS No. | 137075-21-9 |
| Molecular Formula | C17H18ClNO |
| Molecular Weight | 287.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-chloro-N-(3,3-diphenylpropyl)acetamide (CAS 137075-21-9) is a high-purity analytical reference standard with the molecular formula C17H18ClNO and a molecular weight of 287.78 g/mol.
The molecular framework of 2-chloro-N-(3,3-diphenylpropyl)acetamide (C17H18ClNO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H18ClNO |
| Molecular Weight | 287.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 1-(3-Chlorophenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 164226-66-8)
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- 2-Amino-4-morpholin-4-yl-pyrimidine (CAS 861031-56-3)
- 6-(Benzyl(cyclopropyl)amino)nicotinonitrile (CAS 1424339-95-6)
- 1-(5-Fluoro-2-methylphenyl)pentan-1-amine (CAS 1249241-16-4)
- 8-Fluoro-2-(4-isopropylthiazol-2-yl)-7-methoxyquinolin-4-ol (CAS 923604-71-1)
- 4-[4-(Dimethylamino)benzylidene]-2-methyl-1,3-oxazol-5(4H)-one (CAS 1787-23-1)
- Methyl 3-amino-5-nitrobenzoate (CAS 23218-93-1)
- Tributyl(methoxy)silane (CAS 15811-64-0)
- 6-Chloro-7-methyl-2-(trifluoromethyl)-7H-purine (CAS 1095281-91-6)
- Bendamustine Impurity 50 (CAS 5367-53-3)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
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