4-(Bromomethyl)-1-methyl-1H-indole CAS 1371535-79-3
| CAS No. | 1371535-79-3 |
| Molecular Formula | C10H10BrN |
| Molecular Weight | 224.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(Bromomethyl)-1-methyl-1H-indole (C10H10BrN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-(Bromomethyl)-1-methyl-1H-indole (CAS 1371535-79-3) is a high-purity analytical reference standard with the molecular formula C10H10BrN and a molecular weight of 224.10 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Bromomethyl)-1-methyl-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10BrN |
| Molecular Weight | 224.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromomethyl Standards
- 7-(Bromomethyl)-1-methyl-1H-indole (CAS 1130278-03-3)
- 3-(Bromomethyl)-1-methyl-1H-indole (CAS 1161233-34-6)
- 4-(Bromomethyl)-3,5-dimethylbenzonitrile (CAS 1246247-73-3)
- 6-(Bromomethyl)-1-methyl-1H-indole (CAS 1599458-20-4)
- 4-(Bromomethyl)-3-ethylbenzonitrile (CAS 1822666-11-4)
- 5-(Bromomethyl)-1-methyl-1H-indole (CAS 1936732-18-1)
- 2-(Bromomethyl)-1-methyl-1H-indole (CAS 913960-67-5)
- 2-(Bromomethyl)-6-chloro-3-fluoropyridine (CAS 1227509-98-9)
Recommended Standards
- 4-Bromo-3-isopropylbenzonitrile (CAS 1369954-02-8)
- 7-Bromo-1a,2,3,7b-tetrahydro-1H-cyclopropa[c]quinoline (CAS 1404431-48-6)
- 3-Bromo-5-isopropylbenzonitrile (CAS 1369854-24-9)
- 6-Bromo-2,4-dimethyl-1H-indole (CAS 1427363-03-8)
- 3-Methyl-2-oxo-1,2-dihydroquinoline-4-carboxylic Acid (CAS 6625-08-7)
- 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic Acid (CAS 1031619-88-1)
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- 1-Amino-1-deoxy-β-D-mannopyranose (CAS 7388-99-0)
- N-[3-({N-[(3-acetamidophenyl)methyl]4-bromobenzenesulfonamido}methyl)phenyl]acetamide (CAS 866155-46-6)
- Tert-butyl 5-amino-3-methylisothiazole-4-carboxylate (CAS 1539412-74-2)
- 4-Amino-5-(difluoromethyl)-3-hydroxypicolinic acid (CAS 1805082-80-7)
- 4-(1-(Benzo[d][1,3]dioxol-5-yl)-2,5-dimethyl-1h-pyrrol-3-yl)thiazol-2-amine (CAS 733030-79-0)
- N-(1-((S)-2-Amino-3-methylbutanoyl)pyrrolidin-3-yl)acetamide (CAS 1354025-49-2)
- (Thr(PO3H2)231)-Tau Peptide (225-237) trifluoroacetate salt (CAS 1670270-09-3)
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