5-Chloro-2-(6-fluoropyridin-3-yl)-1H-benzoimidazole CAS 1372092-49-3
| CAS No. | 1372092-49-3 |
| Molecular Formula | C12H7ClFN3 |
| Molecular Weight | 247.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-2-(6-fluoropyridin-3-yl)-1H-benzoimidazole.
5-Chloro-2-(6-fluoropyridin-3-yl)-1H-benzoimidazole (CAS 1372092-49-3) is a high-purity analytical reference standard with the molecular formula C12H7ClFN3 and a molecular weight of 247.66 g/mol.
Based on its molecular formula C12H7ClFN3, 5-Chloro-2-(6-fluoropyridin-3-yl)-1H-benzoimidazole contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 247.66 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-2-(6-fluoropyridin-3-yl)-1H-benzoimidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H7ClFN3 |
| Molecular Weight | 247.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 7-Chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 1019918-45-6)
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Recommended Standards
- 4-Acetyl-6-formylpyridine-2-sulfonyl chloride (CAS 1393547-71-1)
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- 2-Acetyl-6-formylpyridine-4-sulfonyl chloride (CAS 1393582-72-3)
- 2-Oxo-3,4-dihydro-2H-1,3-benzoxazine-6-sulfonyl chloride (CAS 1427379-39-2)
- 4-(Difluoromethyl)-5-nitropyridine-3-sulfonamide (CAS 1805300-66-6)
- (S,Z)-3-Ethylidenehexahydropyrrolo[1,2-a]pyrazine-1,4-dione (CAS 114604-89-6)
- N-((5-(4-methoxyphenyl)-1H-pyrazol-4-yl)methyl)cyclopropanamine (CAS 1423517-28-5)
- Morpholine HCl (CAS 10024-89-2)
- 2,5-Dibromothiophene 1,1-Dioxide (CAS 89088-95-9)
- 2-(3,4-Dimethoxyphenyl)-6-ethoxy-7-methoxynaphthalen-1-ol (CAS 85365-76-0)
- N,N'-Bis-(4-chloro-phenyl)-hydrazine (CAS 953-14-0)
- 5-Benzoylisoquinoline (CAS 1270739-12-2)
- N-(5-Fluoro-2-methylphenyl)-3-oxobutanamide (CAS 81761-36-6)
- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
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