2-Ethynyl-3-fluoro-5-methylpyridine CAS 1372103-91-7
| CAS No. | 1372103-91-7 |
| Molecular Formula | C8H6FN |
| Molecular Weight | 135.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Ethynyl-3-fluoro-5-methylpyridine (CAS 1372103-91-7), a certified reference material (molecular formula C8H6FN, MW 135.14 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 2-Ethynyl-3-fluoro-5-methylpyridine is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 135.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Ethynyl-3-fluoro-5-methylpyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6FN |
| Molecular Weight | 135.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethynyl Standards
- 5-Ethynyl-2-fluoroaniline (CAS 1010422-58-8)
- 6-Ethynyl-3-fluoro-2-methylpyridine (CAS 1256792-43-4)
- 2-Ethynyl-5-fluoro-4-methylpyridine (CAS 1256792-71-8)
- 3-Ethynyl-5-fluoroaniline (CAS 1296271-79-8)
- 2-Ethynyl-5-fluoro-3-methylpyridine (CAS 1372103-93-9)
- 3-Ethynyl-5-fluoro-4-methylpyridine (CAS 1382850-26-1)
- 2-Ethynyl-3-fluoro-6-methylpyridine (CAS 1824076-35-8)
- 4-Ethynyl-2-fluoro-3-methylpyridine (CAS 1824113-32-7)
Recommended Standards
- 2-Fluoro-6-(prop-1-yn-1-yl)pyridine (CAS 143651-24-5)
- N-Nitroso-N-methyl-3-aminopropionic Acid-d3 (CAS 1215691-18-1)
- 2,2-Dimethyl-1,3-dioxolane-13C3-4-methanol (CAS 1436560-86-9)
- Isocyanato(methanesulfonyl)methane (CAS 1161826-12-5)
- 4-ethynyl-1-tetrahydropyran-4-yl-pyrazole (CAS 2098009-40-4)
- 5-Chloro-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-amine (CAS 1261680-82-3)
- 2-Amino-2-cyano-N-(2-morpholinoethyl)acetamide (CAS 1214639-32-3)
- 2-Phenoxy-N-(2-(2-(p-tolyl)thiazol-4-yl)ethyl)acetamide (CAS 896614-39-4)
- 1,3-Dibromo-5-(dibromomethyl)benzene (CAS 256386-08-0)
- 1-(3-Chlorophenyl)-3-(2-methyl-6-(trifluoromethyl)pyridin-3-yl)urea (CAS 1858256-58-2)
- 3A,4,7,7a-tetrahydro-1H-4,7-methanoisoindol-2(3H)-amine (CAS 21936-74-3)
- Trazodone Impurity 108 (CAS CATO-C4X-1772108)
- 1-(5-Chloropyrimidin-2-yl)cyclopropan-1-amine hydrochloride (CAS 1443468-17-4)
- Semaglutide Impurity 121 X Sodium Salt (CAS CATO-C4X-2226121)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com