Voriconazole EP Impurity D(Voriconazole Related Compound B) CAS 137234-63-0
| CAS No. | 137234-63-0 |
| Molecular Formula | C16H14F3N5O |
| Molecular Weight | 349.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Voriconazole EP Impurity D(Voriconazole Related Compound B) (CAS 137234-63-0, C16H14F3N5O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C16H14F3N5O, Voriconazole EP Impurity D(Voriconazole Related Compound B) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 349.31 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Voriconazole EP Impurity D(Voriconazole Related Compound B) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14F3N5O |
| Molecular Weight | 349.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Voriconazole Standards
- Voriconazole (CAS 137234-62-9)
- Voriconazole Impurity 10 (CAS 239807-03-5)
- Voriconazole Impurity 30 (CAS 239807-04-6)
- Voriconazole Impurity 60 (CAS CATO-C4X-136660)
- (±)-Voriconazole-d3 (Mixture of Enantiomers) (CAS CATO-C4X-136613)
- Voriconazole-d3 (CAS 1217661-14-7)
- Voriconazole-d3 (CAS 137234-62-9 (unlabelled))
- Voriconazole Impurity 67 (CAS CATO-C4X-136667)
Recommended Standards
- 伏立康唑杂质57 (CAS CATO-C4X-136657)
- Pantoprazole Impurity 50 (CAS CATO-C4X-139950)
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- 6-(4-Fluorophenyl)-4-imino-3-phenyl-1,3,4,7-tetrahydropyrimido[5,4-d]pyrimidine-2,8-dione (CAS 1119391-90-0)
- Meglumine impurity 6 (CAS 62137-31-9)
- Levofloxacin Impurity 96 (CAS CATO-C4X-137196)
- Malic Acid impurity 16 (CAS CATO-C4X-250916)
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- (Bicyclo[3.1.0]hexane-1,5-diyl)dimethanol (CAS 103478-23-5)
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- Boc-Cholecystokinin Octapeptide (desulfated) (A-1295.0001) (CAS 25687-34-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com