Voriconazole Impurity 16 CAS 137234-74-3
| CAS No. | 137234-74-3 |
| Molecular Formula | C6H6ClFN2 |
| Molecular Weight | 160.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C6H6ClFN2, Voriconazole Impurity 16 contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 160.58 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Voriconazole Impurity 16 (CAS 137234-74-3), a pharmacopoeial impurity reference standard (molecular formula C6H6ClFN2, MW 160.58 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6ClFN2 |
| Molecular Weight | 160.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Voriconazole Standards
- Voriconazole Impurity 53 (CAS 759-67-1)
- Voriconazole Impurity 48 (CAS 1403893-61-7)
- Voriconazole Impurity 90 (CAS CATO-C4X-136690)
- Voriconazole Impurity 85 (CAS CATO-C4X-136685)
- Voriconazole Impurity 62 (CAS 6869-07-4)
- Voriconazole Impurity 92 (CAS 145240-42-2)
- Voriconazole Impurity 32 (CAS 180287-02-9)
- Voriconazole Impurity 24 (CAS 898044-55-8)
Recommended Standards
- 6-Chloro-5-fluoro-4-methylpyridin-3-amine (CAS 2201101-41-7)
- 2-Chlorobenzoic-d4 Acid (CAS 1219795-28-4)
- 6-Chloro-3-fluoro-4-methylpyridin-2-amine (CAS 2850301-01-6)
- 3-Chlorobenzoic acid-d4 (CAS 2098655-72-0)
- (3R,4S,5R)-Ascorbic Acid EP Impurity C (CAS 21675-47-8)
- Pirfenidone Impurity 24 (CAS 912570-13-9)
- Vilanterol Impurity C05 (CAS 503068-37-9)
- 2-Amino-4-(4-chloro-3,5-dimethyl-1h-pyrazol-1-yl)butanamide (CAS 1310096-50-4)
- 3-(tert-Butylsulfonyl)azetidine hydrochloride (CAS 1820664-96-7)
- 1-Cyclododecyl-3-mesityl-1H-imidazol-3-ium acetate (CAS 1583243-87-1)
- 1-(Tosyloxy)-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid (CAS 2803338-38-5)
- 2-(5-Bromo-4-chloronaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2621933-85-3)
- 2-cyclopropyl-3-methylcyclopropane-1-carboxylic acid (CAS 1560282-93-0)
- Semaglutide impurity 24 (CAS CATO-C4X-222624)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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