1-Benzyl-3-(chloromethyl)-3-methylazetidin-2-one CAS 137266-58-1
| CAS No. | 137266-58-1 |
| Molecular Formula | C12H14ClNO |
| Molecular Weight | 223.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 1-Benzyl-3-(chloromethyl)-3-methylazetidin-2-one (CAS 137266-58-1), a certified reference material (molecular formula C12H14ClNO, MW 223.70 g/mol) for analytical method development and quality control.
1-Benzyl-3-(chloromethyl)-3-methylazetidin-2-one (C12H14ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14ClNO |
| Molecular Weight | 223.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Benzyl Standards
- (4-(Chloromethyl)phenyl)(pyrrolidin-1-yl)methanone (CAS 929972-98-5)
- 4-(chloromethyl)-N,N-dimethylfuran-2-sulfonamide (CAS 1423033-85-5)
- 2-(Chloromethyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide (CAS 935862-81-0)
- 5-(chloromethyl)-N,N-dimethylfuran-2-sulfonamide (CAS 56038-68-7)
- 4-Chloromethyl-5-methyl-2-phenylthiazole (CAS 178611-25-1)
- 2-(Chloromethyl)-4-(4-methylphenyl)-1,3-thiazole (CAS 921102-01-4)
- 2-benzyl-4-(chloromethyl)-1,3-thiazole (CAS 36916-36-6)
- 4-(Chloromethyl)-2-(4-methylphenyl)-1,3-thiazole (CAS 35199-18-9)
Recommended Standards
- 1-[(2-chlorophenyl)methyl]piperidin-4-one (CAS 135576-51-1)
- 4-Chloro-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran] (CAS 1412906-69-4)
- 1-benzoyl-3-(chloromethyl)pyrrolidine (CAS 1339906-62-5)
- 1-(2-Chlorobenzyl)pyrrolidine-3-carbaldehyde (CAS 1447962-27-7)
- 2-(2-naphthylmethoxy)benzaldehyde (CAS 872183-48-7)
- 5-(5-Chloro-2-thienyl)-7-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride (CAS 863435-88-5)
- 2-mercapto-4,5,6-trimethylnicotinamide (CAS 730973-42-9)
- 4,7-Methano-1H-indene, 3a,4,7,7a-tetrahydro-, polymer with ethene and 1-propene (CAS 25034-71-3)
- Methyl 5,5,7,7-tetramethyl-2-(thiophene-2-carboxamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (CAS 887900-27-8)
- 2-[3-(Trifluoromethyl)benzenesulfonamido]propanoic acid (CAS 250714-51-3)
- 6-Chloro-3,3-dimethyl-2,3-dihydroimidazo[1,5-a]pyridine-1,5-dione (CAS 1849591-66-7)
- Tadalafil Impurity 69 (CAS CATO-C4X-108769)
- 4-chloro-2-cyclopropyl-5-methoxy-6-methylpyrimidine (CAS 1803603-32-8)
- Liraglutide Impurity 5 TFA Salt (CAS CATO-C4X-19925)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com